GO Annotations Graph

• Symbol: Mcrs1
• Name: microspherule protein 1
• ID: MGI:1858420

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0002151	G-quadruplex RNA binding	ISO	J:164563
Molecular Function	GO:0034046	poly(G) binding	ISO	J:164563
Molecular Function	GO:0008266	poly(U) RNA binding	ISO	J:164563
Molecular Function	GO:0010521	telomerase inhibitor activity	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:155856
Cellular Component	GO:0000123	histone acetyltransferase complex	ISO	J:164563
Cellular Component	GO:0031011	Ino80 complex	ISO	J:164563
Cellular Component	GO:0071339	MLL1 complex	ISO	J:164563
Cellular Component	GO:0044545	NSL complex	ISO	J:164563
Cellular Component	GO:0044545	NSL complex	IBA	J:265628
Cellular Component	GO:0005730	nucleolus	ISO	J:164563
Cellular Component	GO:0005730	nucleolus	ISO	J:155856
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0043204	perikaryon	ISO	J:155856
Cellular Component	GO:0005844	polysome	ISO	J:155856
Biological Process	GO:0006325	chromatin organization	IEA	J:60000
Biological Process	GO:0006338	chromatin remodeling	ISO	J:164563
Biological Process	GO:0006974	DNA damage response	IEA	J:60000
Biological Process	GO:0006310	DNA recombination	IEA	J:60000
Biological Process	GO:0006281	DNA repair	IEA	J:60000
Biological Process	GO:0043984	histone H4-K16 acetylation	ISO	J:164563
Biological Process	GO:0043981	histone H4-K5 acetylation	ISO	J:164563
Biological Process	GO:0043982	histone H4-K8 acetylation	ISO	J:164563
Biological Process	GO:0051974	negative regulation of telomerase activity	ISO	J:164563
Biological Process	GO:1904357	negative regulation of telomere maintenance via telomere lengthening	ISO	J:164563
Biological Process	GO:0045739	positive regulation of DNA repair	IDA	J:221224
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	NAS	J:313850
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0051571	positive regulation of histone H3-K4 methylation	ISO	J:164563
Biological Process	GO:1904751	positive regulation of protein localization to nucleolus	ISO	J:164563
Biological Process	GO:1904507	positive regulation of telomere maintenance in response to DNA damage	IMP	J:221224
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0051726	regulation of cell cycle	ISO	J:164563
Biological Process	GO:0033044	regulation of chromosome organization	ISO	J:164563
Biological Process	GO:0006282	regulation of DNA repair	IDA	J:221224
Biological Process	GO:0006275	regulation of DNA replication	ISO	J:164563
Biological Process	GO:0060382	regulation of DNA strand elongation	ISO	J:164563
Biological Process	GO:1900095	regulation of dosage compensation by inactivation of X chromosome	IDA	J:313850
Biological Process	GO:0045995	regulation of embryonic development	IMP	J:221224
Biological Process	GO:0000723	telomere maintenance	IMP	J:221224