GO Annotations Graph

• Symbol: Pla2g6
• Name: phospholipase A2, group VI
• ID: MGI:1859152

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0043008	ATP-dependent protein binding	ISO	J:155856
Molecular Function	GO:0047499	calcium-independent phospholipase A2 activity	IMP	J:144546
Molecular Function	GO:0047499	calcium-independent phospholipase A2 activity	ISO	J:155856
Molecular Function	GO:0047499	calcium-independent phospholipase A2 activity	IMP	J:133472
Molecular Function	GO:0047499	calcium-independent phospholipase A2 activity	ISO	J:164563
Molecular Function	GO:0047499	calcium-independent phospholipase A2 activity	IBA	J:265628
Molecular Function	GO:0005516	calmodulin binding	IEA	J:60000
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0004622	lysophospholipase activity	ISO	J:164563
Molecular Function	GO:0102991	myristoyl-CoA hydrolase activity	IEA	J:72245
Molecular Function	GO:0016290	palmitoyl-CoA hydrolase activity	IMP	J:144546
Molecular Function	GO:0016290	palmitoyl-CoA hydrolase activity	ISO	J:164563
Molecular Function	GO:0016290	palmitoyl-CoA hydrolase activity	ISO	J:155856
Molecular Function	GO:0016290	palmitoyl-CoA hydrolase activity	IBA	J:265628
Molecular Function	GO:0102545	phosphatidyl phospholipase B activity	IEA	J:72245
Molecular Function	GO:0004623	phospholipase A2 activity	IEA	J:72245
Molecular Function	GO:0019901	protein kinase binding	ISO	J:155856
Molecular Function	GO:0017171	serine hydrolase activity	IDA	J:116945
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0034451	centriolar satellite	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005739	mitochondrion	ISO	J:155856
Cellular Component	GO:0005739	mitochondrion	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Biological Process	GO:0019731	antibacterial humoral response	ISO	J:164563
Biological Process	GO:0035965	cardiolipin acyl-chain remodeling	ISO	J:155856
Biological Process	GO:0035965	cardiolipin acyl-chain remodeling	ISO	J:164563
Biological Process	GO:0035965	cardiolipin acyl-chain remodeling	IBA	J:265628
Biological Process	GO:0032049	cardiolipin biosynthetic process	ISO	J:164563
Biological Process	GO:0006935	chemotaxis	IEA	J:60000
Biological Process	GO:0006629	lipid metabolic process	IEA	J:72247
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0007613	memory	ISO	J:155856
Biological Process	GO:0051967	negative regulation of synaptic transmission, glutamatergic	ISO	J:155856
Biological Process	GO:0034638	phosphatidylcholine catabolic process	ISO	J:164563
Biological Process	GO:0090238	positive regulation of arachidonic acid secretion	ISO	J:155856
Biological Process	GO:2000304	positive regulation of ceramide biosynthetic process	ISO	J:155856
Biological Process	GO:2000304	positive regulation of ceramide biosynthetic process	IBA	J:265628
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	ISO	J:155856
Biological Process	GO:0045921	positive regulation of exocytosis	ISO	J:155856
Biological Process	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus	ISO	J:155856
Biological Process	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus	IMP	J:133472
Biological Process	GO:0090037	positive regulation of protein kinase C signaling	ISO	J:155856
Biological Process	GO:0001934	positive regulation of protein phosphorylation	ISO	J:155856
Biological Process	GO:0090200	positive regulation of release of cytochrome c from mitochondria	ISO	J:155856
Biological Process	GO:1901339	regulation of store-operated calcium channel activity	ISO	J:155856
Biological Process	GO:0034976	response to endoplasmic reticulum stress	ISO	J:155856
Biological Process	GO:0014832	urinary bladder smooth muscle contraction	ISO	J:155856
Biological Process	GO:0042311	vasodilation	ISO	J:155856