GO Annotations Graph

• Symbol: Irf7
• Name: interferon regulatory factor 7
• ID: MGI:1859212

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	IDA	J:235021
Molecular Function	GO:0003677	DNA binding	ISO	J:164563
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IEA	J:72247
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IMP	J:235021
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IDA	J:188556
Molecular Function	GO:0005515	protein binding	IPI	J:107628
Molecular Function	GO:0005515	protein binding	IPI	J:221417
Molecular Function	GO:0005515	protein binding	IPI	J:102933
Molecular Function	GO:0005515	protein binding	IPI	J:180378
Molecular Function	GO:0005515	protein binding	IPI	J:205872
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0000976	transcription cis-regulatory region binding	IEA	J:72247
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Biological Process	GO:0051607	defense response to virus	ISO	J:164563
Biological Process	GO:0051607	defense response to virus	IMP	J:235021
Biological Process	GO:0002376	immune system process	IBA	J:265628
Biological Process	GO:0016064	immunoglobulin mediated immune response	IMP	J:97662
Biological Process	GO:0045087	innate immune response	IEA	J:60000
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IMP	J:235021
Biological Process	GO:0032727	positive regulation of interferon-alpha production	ISO	J:164563
Biological Process	GO:0032727	positive regulation of interferon-alpha production	TAS	J:184127
Biological Process	GO:0032728	positive regulation of interferon-beta production	ISO	J:164563
Biological Process	GO:0032728	positive regulation of interferon-beta production	TAS	J:184127
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0032481	positive regulation of type I interferon production	ISO	J:164563
Biological Process	GO:0032481	positive regulation of type I interferon production	IGI	J:205872
Biological Process	GO:0060340	positive regulation of type I interferon-mediated signaling pathway	IMP	J:123411
Biological Process	GO:0002819	regulation of adaptive immune response	ISO	J:164563
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0010468	regulation of gene expression	IGI	J:191073
Biological Process	GO:0010468	regulation of gene expression	IGI	J:191073
Biological Process	GO:0010468	regulation of gene expression	IGI	J:191073
Biological Process	GO:0010468	regulation of gene expression	IGI	J:191073
Biological Process	GO:0045088	regulation of innate immune response	TAS	J:97662
Biological Process	GO:0034124	regulation of MyD88-dependent toll-like receptor signaling pathway	IMP	J:97662
Biological Process	GO:0034127	regulation of MyD88-independent toll-like receptor signaling pathway	IMP	J:97662
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0032606	type I interferon production	IMP	J:97662
Biological Process	GO:0060337	type I interferon-mediated signaling pathway	IMP	J:235021