GO Annotations Graph

• Symbol: Sh3glb1
• Name: SH3-domain GRB2-like B1 (endophilin)
• ID: MGI:1859730

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005504	fatty acid binding	IDA	J:81675
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0008289	lipid binding	IEA	J:60000
Molecular Function	GO:0042171	lysophosphatidic acid acyltransferase activity	IDA	J:81675
Molecular Function	GO:0005515	protein binding	IPI	J:81675
Molecular Function	GO:0005515	protein binding	IPI	J:102178
Molecular Function	GO:0005515	protein binding	IPI	J:81675
Molecular Function	GO:0005515	protein binding	IPI	J:81675
Molecular Function	GO:0005515	protein binding	IPI	J:129990
Molecular Function	GO:0005515	protein binding	IPI	J:129990
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Cellular Component	GO:0000421	autophagosome membrane	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:69889
Cellular Component	GO:0005769	early endosome	ISO	J:155856
Cellular Component	GO:0005783	endoplasmic reticulum	IC	J:81675
Cellular Component	GO:0005794	Golgi apparatus	IEA	J:60000
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0016020	membrane	IBA	J:265628
Cellular Component	GO:0016020	membrane	IDA	J:81675
Cellular Component	GO:0030496	midbody	ISO	J:164563
Cellular Component	GO:0005740	mitochondrial envelope	ISO	J:69889
Cellular Component	GO:0005741	mitochondrial outer membrane	IEA	J:60000
Cellular Component	GO:0005739	mitochondrion	IEA	J:60000
Cellular Component	GO:0043005	neuron projection	ISO	J:155856
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Cellular Component	GO:0032991	protein-containing complex	IDA	J:129990
Cellular Component	GO:0008021	synaptic vesicle	ISO	J:155856
Biological Process	GO:0051084	'de novo' post-translational protein folding	IDA	J:102178
Biological Process	GO:0006915	apoptotic process	ISO	J:69889
Biological Process	GO:0048102	autophagic cell death	ISO	J:164563
Biological Process	GO:0048102	autophagic cell death	IMP	J:129990
Biological Process	GO:0034198	cellular response to amino acid starvation	ISO	J:164563
Biological Process	GO:0042149	cellular response to glucose starvation	ISO	J:164563
Biological Process	GO:0090148	membrane fission	ISO	J:164563
Biological Process	GO:0061024	membrane organization	IBA	J:265628
Biological Process	GO:0007005	mitochondrion organization	IMP	J:206937
Biological Process	GO:1902254	negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator	IMP	J:206937
Biological Process	GO:0006654	phosphatidic acid biosynthetic process	IDA	J:81675
Biological Process	GO:0008654	phospholipid biosynthetic process	IDA	J:81675
Biological Process	GO:2000786	positive regulation of autophagosome assembly	IMP	J:220511
Biological Process	GO:2000786	positive regulation of autophagosome assembly	ISO	J:164563
Biological Process	GO:0010508	positive regulation of autophagy	ISO	J:164563
Biological Process	GO:0010508	positive regulation of autophagy	IMP	J:129990
Biological Process	GO:1903861	positive regulation of dendrite extension	ISO	J:155856
Biological Process	GO:0050775	positive regulation of dendrite morphogenesis	ISO	J:155856
Biological Process	GO:1902255	positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator	IDA	J:206937
Biological Process	GO:1903527	positive regulation of membrane tubulation	ISO	J:164563
Biological Process	GO:0051388	positive regulation of neurotrophin TRK receptor signaling pathway	ISO	J:155856
Biological Process	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	IMP	J:129990
Biological Process	GO:1900740	positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	IMP	J:102178
Biological Process	GO:0031334	positive regulation of protein-containing complex assembly	ISO	J:164563
Biological Process	GO:1903778	protein localization to vacuolar membrane	IMP	J:220511
Biological Process	GO:1903778	protein localization to vacuolar membrane	ISO	J:164563
Biological Process	GO:0032801	receptor catabolic process	ISO	J:164563
Biological Process	GO:0032465	regulation of cytokinesis	ISO	J:164563
Biological Process	GO:2000641	regulation of early endosome to late endosome transport	ISO	J:155856