GO Annotations Graph

• Symbol: Msh4
• Name: mutS homolog 4
• ID: MGI:1860077

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0140664	ATP-dependent DNA damage sensor activity	IEA	J:72247
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0003690	double-stranded DNA binding	IBA	J:265628
Molecular Function	GO:0030983	mismatched DNA binding	IEA	J:72247
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Cellular Component	GO:0005694	chromosome	IDA	J:268520
Cellular Component	GO:0000793	condensed chromosome	IDA	J:62204
Cellular Component	GO:0000794	condensed nuclear chromosome	IDA	J:131722
Cellular Component	GO:0000794	condensed nuclear chromosome	IDA	J:195265
Cellular Component	GO:0000794	condensed nuclear chromosome	IDA	J:182264
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-912462
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-912487
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:62204
Cellular Component	GO:0005634	nucleus	IDA	J:270644
Cellular Component	GO:0005713	recombination nodule	IDA	J:236226
Cellular Component	GO:0000795	synaptonemal complex	IDA	J:62204
Cellular Component	GO:0000795	synaptonemal complex	ISS	J:113188
Cellular Component	GO:0000795	synaptonemal complex	IDA	J:104493
Biological Process	GO:0007292	female gamete generation	IMP	J:62204
Biological Process	GO:0007129	homologous chromosome pairing at meiosis	IMP	J:93127
Biological Process	GO:0007129	homologous chromosome pairing at meiosis	IMP	J:93127
Biological Process	GO:0007129	homologous chromosome pairing at meiosis	IMP	J:62204
Biological Process	GO:0051321	meiotic cell cycle	IDA	J:62204
Biological Process	GO:0051321	meiotic cell cycle	IMP	J:62204
Biological Process	GO:0006298	mismatch repair	IEA	J:72247
Biological Process	GO:0001541	ovarian follicle development	IMP	J:62204
Biological Process	GO:0007131	reciprocal meiotic recombination	IBA	J:265628
Biological Process	GO:0007283	spermatogenesis	IMP	J:62204