GO Annotations Graph

• Symbol: Gabbr1
• Name: gamma-aminobutyric acid type B receptor subunit 1
• ID: MGI:1860139

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:1990430	extracellular matrix protein binding	ISO	J:155856
Molecular Function	GO:0004965	G protein-coupled GABA receptor activity	ISO	J:164563
Molecular Function	GO:0004965	G protein-coupled GABA receptor activity	ISO	J:164563
Molecular Function	GO:0004965	G protein-coupled GABA receptor activity	ISO	J:155856
Molecular Function	GO:0004965	G protein-coupled GABA receptor activity	IBA	J:265628
Molecular Function	GO:0099579	G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	IMP	J:70558
Molecular Function	GO:0099579	G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	EXP	J:70558
Molecular Function	GO:0099579	G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	EXP	J:70558
Molecular Function	GO:0099579	G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	IDA	J:70558
Molecular Function	GO:0099579	G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	IMP	J:70558
Molecular Function	GO:0099579	G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	IDA	J:70558
Molecular Function	GO:0150047	G protein-coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential	IDA	J:326498
Molecular Function	GO:0150047	G protein-coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential	IMP	J:326498
Molecular Function	GO:0150047	G protein-coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential	NAS	J:326498
Molecular Function	GO:0150047	G protein-coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential	IDA	J:326498
Molecular Function	GO:0004930	G protein-coupled receptor activity	IEA	J:72247
Molecular Function	GO:0004930	G protein-coupled receptor activity	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:88780
Molecular Function	GO:0005515	protein binding	IPI	J:161971
Molecular Function	GO:0046982	protein heterodimerization activity	ISO	J:155856
Cellular Component	GO:0030673	axolemma	ISO	J:155856
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IDA	J:88780
Cellular Component	GO:0043198	dendritic shaft	ISO	J:155856
Cellular Component	GO:0043197	dendritic spine	ISO	J:155856
Cellular Component	GO:0005789	endoplasmic reticulum membrane	ISO	J:155856
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:1902712	G protein-coupled GABA receptor complex	ISO	J:164563
Cellular Component	GO:0038037	G protein-coupled receptor dimeric complex	IDA	J:161971
Cellular Component	GO:0038039	G protein-coupled receptor heterodimeric complex	ISO	J:164563
Cellular Component	GO:0038039	G protein-coupled receptor heterodimeric complex	IBA	J:265628
Cellular Component	GO:1902710	GABA receptor complex	ISO	J:155856
Cellular Component	GO:0098982	GABA-ergic synapse	ISO	J:155856
Cellular Component	GO:0098982	GABA-ergic synapse	IDA	J:70558
Cellular Component	GO:0098982	GABA-ergic synapse	IMP	J:70558
Cellular Component	GO:0098982	GABA-ergic synapse	EXP	J:70558
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:155856
Cellular Component	GO:0016020	membrane	IDA	J:161971
Cellular Component	GO:0045121	membrane raft	ISO	J:155856
Cellular Component	GO:0031966	mitochondrial membrane	ISO	J:155856
Cellular Component	GO:0043005	neuron projection	ISO	J:155856
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0045211	postsynaptic membrane	ISO	J:155856
Cellular Component	GO:0045211	postsynaptic membrane	IDA	J:161971
Cellular Component	GO:0098793	presynapse	IDA	J:237681
Cellular Component	GO:0042734	presynaptic membrane	ISO	J:155856
Cellular Component	GO:0042734	presynaptic membrane	IDA	J:161971
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IDA	J:70558
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IMP	J:70558
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	EXP	J:70558
Cellular Component	GO:0045202	synapse	IEA	J:60000
Cellular Component	GO:0097060	synaptic membrane	ISO	J:155856
Cellular Component	GO:0008021	synaptic vesicle	ISO	J:155856
Biological Process	GO:0007193	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	ISO	J:164563
Biological Process	GO:0007193	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	ISO	J:155856
Biological Process	GO:0007193	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	ISO	J:73065
Biological Process	GO:0007193	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	ISO	J:73065
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IEA	J:72247
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IEA	J:60000
Biological Process	GO:0007214	gamma-aminobutyric acid signaling pathway	ISO	J:155856
Biological Process	GO:0007214	gamma-aminobutyric acid signaling pathway	ISO	J:164563
Biological Process	GO:0007214	gamma-aminobutyric acid signaling pathway	IBA	J:265628
Biological Process	GO:0007214	gamma-aminobutyric acid signaling pathway	IDA	J:161971
Biological Process	GO:0007194	negative regulation of adenylate cyclase activity	ISO	J:155856
Biological Process	GO:0008285	negative regulation of cell population proliferation	ISO	J:155856
Biological Process	GO:0033602	negative regulation of dopamine secretion	ISO	J:155856
Biological Process	GO:0032811	negative regulation of epinephrine secretion	ISO	J:155856
Biological Process	GO:0014053	negative regulation of gamma-aminobutyric acid secretion	ISO	J:155856
Biological Process	GO:0050805	negative regulation of synaptic transmission	ISO	J:155856
Biological Process	GO:0150099	neuron-glial cell signaling	ISO	J:155856
Biological Process	GO:0001649	osteoblast differentiation	ISO	J:155856
Biological Process	GO:0014049	positive regulation of glutamate secretion	ISO	J:155856
Biological Process	GO:0060124	positive regulation of growth hormone secretion	ISO	J:155856
Biological Process	GO:0014048	regulation of glutamate secretion	ISO	J:155856
Biological Process	GO:0007165	signal transduction	IEA	J:60000
Biological Process	GO:0051932	synaptic transmission, GABAergic	NAS	J:320798