GO Annotations Graph

• Symbol: Sfrp5
• Name: secreted frizzled-related sequence protein 5
• ID: MGI:1860298

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0017147	Wnt-protein binding	IBA	J:265628
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Biological Process	GO:0060070	canonical Wnt signaling pathway	IBA	J:265628
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0060028	convergent extension involved in axis elongation	IGI	J:135313
Biological Process	GO:0060028	convergent extension involved in axis elongation	IGI	J:135313
Biological Process	GO:0048546	digestive tract morphogenesis	IGI	J:147041
Biological Process	GO:0048546	digestive tract morphogenesis	IGI	J:147041
Biological Process	GO:0048546	digestive tract morphogenesis	IGI	J:147041
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	ISO	J:164563
Biological Process	GO:0008285	negative regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0043433	negative regulation of DNA-binding transcription factor activity	ISO	J:164563
Biological Process	GO:0043508	negative regulation of JUN kinase activity	IGI	J:147041
Biological Process	GO:0043508	negative regulation of JUN kinase activity	IGI	J:147041
Biological Process	GO:2000041	negative regulation of planar cell polarity pathway involved in axis elongation	IGI	J:135313
Biological Process	GO:2000041	negative regulation of planar cell polarity pathway involved in axis elongation	IGI	J:135313
Biological Process	GO:2000041	negative regulation of planar cell polarity pathway involved in axis elongation	IGI	J:135313
Biological Process	GO:0051898	negative regulation of protein kinase B signaling	ISO	J:164563
Biological Process	GO:0030178	negative regulation of Wnt signaling pathway	ISO	J:73065
Biological Process	GO:2000057	negative regulation of Wnt signaling pathway involved in digestive tract morphogenesis	ISO	J:164563
Biological Process	GO:0035567	non-canonical Wnt signaling pathway	IBA	J:265628
Biological Process	GO:0003402	planar cell polarity pathway involved in axis elongation	IGI	J:135313
Biological Process	GO:0003402	planar cell polarity pathway involved in axis elongation	IGI	J:135313
Biological Process	GO:0003402	planar cell polarity pathway involved in axis elongation	IGI	J:135313
Biological Process	GO:0090179	planar cell polarity pathway involved in neural tube closure	IGI	J:135313
Biological Process	GO:0090179	planar cell polarity pathway involved in neural tube closure	IGI	J:135313
Biological Process	GO:0090179	planar cell polarity pathway involved in neural tube closure	IGI	J:135313
Biological Process	GO:0036342	post-anal tail morphogenesis	IGI	J:119228
Biological Process	GO:0030510	regulation of BMP signaling pathway	IEA	J:72247
Biological Process	GO:0090175	regulation of establishment of planar polarity	IGI	J:147041
Biological Process	GO:0090175	regulation of establishment of planar polarity	IGI	J:147041
Biological Process	GO:0090175	regulation of establishment of planar polarity	IGI	J:147041
Biological Process	GO:0030111	regulation of Wnt signaling pathway	IEA	J:72247
Biological Process	GO:0016055	Wnt signaling pathway	IEA	J:60000