GO Annotations Graph

• Symbol: Mad2l1
• Name: MAD2 mitotic arrest deficient-like 1
• ID: MGI:1860374

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:305154
Molecular Function	GO:0005515	protein binding	IPI	J:200494
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Cellular Component	GO:0005694	chromosome	IDA	J:121535
Cellular Component	GO:0000775	chromosome, centromeric region	IDA	J:80450
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IDA	J:121560
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0000776	kinetochore	ISO	J:164563
Cellular Component	GO:0000776	kinetochore	ISO	J:164563
Cellular Component	GO:0000776	kinetochore	IBA	J:265628
Cellular Component	GO:0000776	kinetochore	IDA	J:145744
Cellular Component	GO:0000776	kinetochore	IDA	J:148330
Cellular Component	GO:0000776	kinetochore	IDA	J:121560
Cellular Component	GO:0000776	kinetochore	IDA	J:64328
Cellular Component	GO:0033597	mitotic checkpoint complex	ISO	J:164563
Cellular Component	GO:0072686	mitotic spindle	ISO	J:164563
Cellular Component	GO:1990728	mitotic spindle assembly checkpoint MAD1-MAD2 complex	ISO	J:164563
Cellular Component	GO:1990728	mitotic spindle assembly checkpoint MAD1-MAD2 complex	IPI	J:314961
Cellular Component	GO:0044615	nuclear pore nuclear basket	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	IBA	J:265628
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:240155
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:164563
Cellular Component	GO:0000922	spindle pole	IDA	J:121560
Cellular Component	GO:0000922	spindle pole	IDA	J:64328
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0051301	cell division	IEA	J:60000
Biological Process	GO:0051660	establishment of centrosome localization	ISO	J:164563
Biological Process	GO:0000132	establishment of mitotic spindle orientation	ISO	J:164563
Biological Process	GO:0007093	mitotic cell cycle checkpoint signaling	ISO	J:73065
Biological Process	GO:0000070	mitotic sister chromatid segregation	IMP	J:62829
Biological Process	GO:0007094	mitotic spindle assembly checkpoint signaling	ISO	J:164563
Biological Process	GO:0007094	mitotic spindle assembly checkpoint signaling	NAS	J:320291
Biological Process	GO:0007094	mitotic spindle assembly checkpoint signaling	IBA	J:265628
Biological Process	GO:0007094	mitotic spindle assembly checkpoint signaling	ISA	J:62829
Biological Process	GO:0007094	mitotic spindle assembly checkpoint signaling	IMP	J:67456
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0043066	negative regulation of apoptotic process	IMP	J:166080
Biological Process	GO:0045930	negative regulation of mitotic cell cycle	ISO	J:73065
Biological Process	GO:0045841	negative regulation of mitotic metaphase/anaphase transition	TAS	J:79594
Biological Process	GO:0042177	negative regulation of protein catabolic process	ISO	J:164563
Biological Process	GO:1904667	negative regulation of ubiquitin protein ligase activity	ISO	J:164563
Biological Process	GO:0051444	negative regulation of ubiquitin-protein transferase activity	ISO	J:164563
Biological Process	GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint	ISO	J:164563
Biological Process	GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint	IMP	J:166080