GO Annotations Graph

• Symbol: Ddx21
• Name: DExD box helicase 21
• ID: MGI:1860494

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0097322	7SK snRNA binding	ISO	J:164563
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0003725	double-stranded RNA binding	IDA	J:173994
Molecular Function	GO:0004386	helicase activity	IEA	J:72247
Molecular Function	GO:0004386	helicase activity	IEA	J:60000
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0042802	identical protein binding	IDA	J:173994
Molecular Function	GO:0035198	miRNA binding	ISO	J:164563
Molecular Function	GO:0003676	nucleic acid binding	IEA	J:72247
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:278445
Molecular Function	GO:0005515	protein binding	IPI	J:173994
Molecular Function	GO:0005515	protein binding	IPI	J:173994
Molecular Function	GO:0003723	RNA binding	IBA	J:265628
Molecular Function	GO:0003723	RNA binding	ISS	J:62861
Molecular Function	GO:0003724	RNA helicase activity	ISO	J:164563
Molecular Function	GO:0003724	RNA helicase activity	IBA	J:265628
Molecular Function	GO:0003724	RNA helicase activity	ISS	J:62861
Molecular Function	GO:0019843	rRNA binding	ISO	J:164563
Molecular Function	GO:0030515	snoRNA binding	ISO	J:164563
Cellular Component	GO:0110016	B-WICH complex	ISO	J:164563
Cellular Component	GO:0005694	chromosome	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005829	cytosol	IDA	J:173994
Cellular Component	GO:0005739	mitochondrion	NAS	J:173994
Cellular Component	GO:0005730	nucleolus	NAS	J:319968
Cellular Component	GO:0005730	nucleolus	ISO	J:164563
Cellular Component	GO:0005730	nucleolus	IBA	J:265628
Cellular Component	GO:0005730	nucleolus	ISS	J:62861
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISS	J:62861
Biological Process	GO:0006338	chromatin remodeling	NAS	J:320057
Biological Process	GO:0051607	defense response to virus	IEA	J:60000
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0045087	innate immune response	IEA	J:60000
Biological Process	GO:0035066	positive regulation of histone acetylation	NAS	J:319968
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	IMP	J:173994
Biological Process	GO:0002735	positive regulation of myeloid dendritic cell cytokine production	IMP	J:173994
Biological Process	GO:0045943	positive regulation of transcription by RNA polymerase I	NAS	J:319968
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	NAS	J:319696
Biological Process	GO:0045945	positive regulation of transcription by RNA polymerase III	ISO	J:164563
Biological Process	GO:0062176	R-loop processing	ISO	J:164563
Biological Process	GO:0043330	response to exogenous dsRNA	IMP	J:173994
Biological Process	GO:0009615	response to virus	IMP	J:173994
Biological Process	GO:0006364	rRNA processing	IEA	J:60000
Biological Process	GO:0006366	transcription by RNA polymerase II	ISO	J:164563