GO Annotations Graph

• Symbol: Fntb
• Name: farnesyltransferase, CAAX box, beta
• ID: MGI:1861305

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003824	catalytic activity	IEA	J:72247
Molecular Function	GO:0004311	farnesyltranstransferase activity	IMP	J:98944
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0042277	peptide binding	ISO	J:155856
Molecular Function	GO:0004659	prenyltransferase activity	IEA	J:60000
Molecular Function	GO:0004660	protein farnesyltransferase activity	ISO	J:155856
Molecular Function	GO:0004660	protein farnesyltransferase activity	ISO	J:164563
Molecular Function	GO:0004660	protein farnesyltransferase activity	ISO	J:164563
Molecular Function	GO:0004660	protein farnesyltransferase activity	ISO	J:155856
Molecular Function	GO:0004660	protein farnesyltransferase activity	IBA	J:265628
Molecular Function	GO:0008318	protein prenyltransferase activity	IEA	J:72247
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0008270	zinc ion binding	ISO	J:164563
Cellular Component	GO:0005875	microtubule associated complex	ISO	J:164563
Cellular Component	GO:0005965	protein farnesyltransferase complex	ISO	J:164563
Cellular Component	GO:0005965	protein farnesyltransferase complex	IBA	J:265628
Biological Process	GO:0008283	cell population proliferation	IMP	J:98944
Biological Process	GO:0008283	cell population proliferation	IMP	J:98944
Biological Process	GO:0008283	cell population proliferation	IMP	J:98944
Biological Process	GO:0048144	fibroblast proliferation	IMP	J:98944
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0008285	negative regulation of cell population proliferation	IMP	J:98944
Biological Process	GO:0045787	positive regulation of cell cycle	ISO	J:155856
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:155856
Biological Process	GO:0008284	positive regulation of cell population proliferation	IMP	J:98944
Biological Process	GO:0048146	positive regulation of fibroblast proliferation	IMP	J:98944
Biological Process	GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process	ISO	J:155856
Biological Process	GO:0018343	protein farnesylation	IBA	J:265628
Biological Process	GO:0048145	regulation of fibroblast proliferation	IMP	J:199185
Biological Process	GO:0034097	response to cytokine	ISO	J:155856
Biological Process	GO:0010035	response to inorganic substance	ISO	J:155856
Biological Process	GO:0014070	response to organic cyclic compound	ISO	J:155856
Biological Process	GO:0042060	wound healing	IMP	J:98944