GO Annotations Graph

• Symbol: Rab27a
• Name: RAB27A, member RAS oncogene family
• ID: MGI:1861441

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003925	G protein activity	IEA	J:72245
Molecular Function	GO:0019003	GDP binding	ISO	J:164563
Molecular Function	GO:0005525	GTP binding	IDA	J:155185
Molecular Function	GO:0005525	GTP binding	ISO	J:164563
Molecular Function	GO:0003924	GTPase activity	IDA	J:155185
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0031489	myosin V binding	IPI	J:67601
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:75312
Molecular Function	GO:0005515	protein binding	IPI	J:75312
Molecular Function	GO:0005515	protein binding	IPI	J:75312
Molecular Function	GO:0005515	protein binding	IPI	J:133380
Molecular Function	GO:0005515	protein binding	IPI	J:75312
Molecular Function	GO:0005515	protein binding	IPI	J:155184
Molecular Function	GO:0005515	protein binding	IPI	J:166024
Molecular Function	GO:0005515	protein binding	IPI	J:150917
Molecular Function	GO:0005515	protein binding	IPI	J:76844
Molecular Function	GO:0005515	protein binding	IPI	J:75312
Molecular Function	GO:0005515	protein binding	IPI	J:169802
Molecular Function	GO:0005515	protein binding	IPI	J:155185
Molecular Function	GO:0005515	protein binding	IPI	J:155185
Molecular Function	GO:0005515	protein binding	IPI	J:278051
Molecular Function	GO:0005515	protein binding	IPI	J:83162
Molecular Function	GO:0005515	protein binding	IPI	J:83162
Molecular Function	GO:0005515	protein binding	IPI	J:83108
Molecular Function	GO:0005515	protein binding	IPI	J:83162
Molecular Function	GO:0005515	protein binding	IPI	J:83162
Molecular Function	GO:0005515	protein binding	IPI	J:87907
Molecular Function	GO:0005515	protein binding	IPI	J:83162
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:155856
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:155856
Cellular Component	GO:0030425	dendrite	ISO	J:164563
Cellular Component	GO:0005768	endosome	IEA	J:60000
Cellular Component	GO:0070382	exocytic vesicle	ISO	J:164563
Cellular Component	GO:0005794	Golgi apparatus	IDA	J:89391
Cellular Component	GO:0005622	intracellular anatomical structure	ISS	J:63231
Cellular Component	GO:0005770	late endosome	ISO	J:164563
Cellular Component	GO:0005764	lysosome	ISO	J:164563
Cellular Component	GO:0042470	melanosome	ISO	J:164563
Cellular Component	GO:0042470	melanosome	ISO	J:155856
Cellular Component	GO:0042470	melanosome	IDA	J:76844
Cellular Component	GO:0042470	melanosome	IBA	J:265628
Cellular Component	GO:0042470	melanosome	IDA	J:197308
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0032585	multivesicular body membrane	ISO	J:164563
Cellular Component	GO:0001750	photoreceptor outer segment	IDA	J:76844
Cellular Component	GO:0030141	secretory granule	ISO	J:155856
Cellular Component	GO:0030141	secretory granule	IMP	J:111253
Cellular Component	GO:0030667	secretory granule membrane	ISO	J:155856
Cellular Component	GO:0033093	Weibel-Palade body	ISO	J:155856
Biological Process	GO:0019882	antigen processing and presentation	ISO	J:164563
Biological Process	GO:0007596	blood coagulation	IMP	J:63231
Biological Process	GO:0097278	complement-dependent cytotoxicity	ISO	J:164563
Biological Process	GO:0043316	cytotoxic T cell degranulation	IMP	J:111253
Biological Process	GO:0006887	exocytosis	ISO	J:164563
Biological Process	GO:1990182	exosomal secretion	ISO	J:164563
Biological Process	GO:0030318	melanocyte differentiation	IMP	J:29467
Biological Process	GO:0030318	melanocyte differentiation	IMP	MGI:MGI:52947
Biological Process	GO:0032400	melanosome localization	ISO	J:164563
Biological Process	GO:0032402	melanosome transport	IMP	J:111253
Biological Process	GO:0036257	multivesicular body organization	ISO	J:164563
Biological Process	GO:0071985	multivesicular body sorting pathway	ISO	J:164563
Biological Process	GO:0043320	natural killer cell degranulation	IMP	J:111253
Biological Process	GO:0051875	pigment granule localization	IMP	J:91408
Biological Process	GO:0051875	pigment granule localization	IMP	J:94444
Biological Process	GO:0051904	pigment granule transport	IMP	J:94444
Biological Process	GO:0043473	pigmentation	IMP	J:29467
Biological Process	GO:1903435	positive regulation of constitutive secretory pathway	ISO	J:164563
Biological Process	GO:0045921	positive regulation of exocytosis	ISO	J:164563
Biological Process	GO:0045921	positive regulation of exocytosis	IBA	J:265628
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:164563
Biological Process	GO:0050766	positive regulation of phagocytosis	ISO	J:164563
Biological Process	GO:1903428	positive regulation of reactive oxygen species biosynthetic process	ISO	J:164563
Biological Process	GO:1903307	positive regulation of regulated secretory pathway	ISO	J:164563
Biological Process	GO:0016192	vesicle-mediated transport	IBA	J:265628
Biological Process	GO:0016192	vesicle-mediated transport	IMP	J:63231