GO Annotations Graph

• Symbol: Cxcl13
• Name: C-X-C motif chemokine ligand 13
• ID: MGI:1888499

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0031735	CCR10 chemokine receptor binding	ISO	J:164563
Molecular Function	GO:0008009	chemokine activity	IDA	J:119527
Molecular Function	GO:0008009	chemokine activity	ISO	J:164563
Molecular Function	GO:0008009	chemokine activity	IBA	J:265628
Molecular Function	GO:0045236	CXCR chemokine receptor binding	IBA	J:265628
Molecular Function	GO:0048248	CXCR3 chemokine receptor binding	ISO	J:164563
Molecular Function	GO:0031724	CXCR5 chemokine receptor binding	ISO	J:164563
Molecular Function	GO:0031724	CXCR5 chemokine receptor binding	IDA	J:172920
Molecular Function	GO:0005125	cytokine activity	IEA	J:60000
Molecular Function	GO:0017134	fibroblast growth factor binding	ISO	J:164563
Molecular Function	GO:0008201	heparin binding	ISO	J:164563
Molecular Function	GO:0048018	receptor ligand activity	ISO	J:164563
Cellular Component	GO:0005576	extracellular region	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Cellular Component	GO:0005615	extracellular space	IDA	J:194920
Biological Process	GO:0090630	activation of GTPase activity	IDA	J:119527
Biological Process	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide	ISO	J:164563
Biological Process	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide	IBA	J:265628
Biological Process	GO:0035754	B cell chemotaxis	IMP	J:119527
Biological Process	GO:0035754	B cell chemotaxis	ISO	J:164563
Biological Process	GO:0035769	B cell chemotaxis across high endothelial venule	IDA	J:119527
Biological Process	GO:0007166	cell surface receptor signaling pathway	ISO	J:164563
Biological Process	GO:0007267	cell-cell signaling	ISO	J:164563
Biological Process	GO:0071222	cellular response to lipopolysaccharide	IBA	J:265628
Biological Process	GO:0070098	chemokine-mediated signaling pathway	NAS	J:119527
Biological Process	GO:0070098	chemokine-mediated signaling pathway	IBA	J:265628
Biological Process	GO:0006935	chemotaxis	IEA	J:72247
Biological Process	GO:0006935	chemotaxis	IEA	J:60000
Biological Process	GO:0006952	defense response	IEA	J:72247
Biological Process	GO:0042742	defense response to bacterium	ISO	J:164563
Biological Process	GO:0035768	endothelial cell chemotaxis to fibroblast growth factor	ISO	J:164563
Biological Process	GO:0006955	immune response	IEA	J:72247
Biological Process	GO:0006954	inflammatory response	IBA	J:265628
Biological Process	GO:0031640	killing of cells of another organism	ISO	J:164563
Biological Process	GO:0048535	lymph node development	IDA	J:157747
Biological Process	GO:0048535	lymph node development	IMP	J:83288
Biological Process	GO:0002518	lymphocyte chemotaxis across high endothelial venule	IMP	J:119527
Biological Process	GO:2000545	negative regulation of endothelial cell chemotaxis to fibroblast growth factor	ISO	J:164563
Biological Process	GO:0030593	neutrophil chemotaxis	IBA	J:265628
Biological Process	GO:0033634	positive regulation of cell-cell adhesion mediated by integrin	IDA	J:119527
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	ISO	J:164563
Biological Process	GO:0033625	positive regulation of integrin activation	IDA	J:119527
Biological Process	GO:0010820	positive regulation of T cell chemotaxis	ISO	J:164563