GO Annotations Graph

• Symbol: Icmt
• Name: isoprenylcysteine carboxyl methyltransferase
• ID: MGI:1888594

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008140	cAMP response element binding protein binding	IMP	J:88170
Molecular Function	GO:0008168	methyltransferase activity	IEA	J:60000
Molecular Function	GO:0004671	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity	ISO	J:164563
Molecular Function	GO:0004671	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity	ISO	J:155856
Molecular Function	GO:0004671	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity	IBA	J:265628
Molecular Function	GO:0004671	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity	IMP	J:67598
Molecular Function	GO:0004671	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity	IMP	J:62754
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0005783	endoplasmic reticulum	IBA	J:265628
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:73065
Cellular Component	GO:0016020	membrane	ISO	J:155856
Biological Process	GO:0030282	bone mineralization	IGI	J:199185
Biological Process	GO:0006481	C-terminal protein methylation	ISO	J:155856
Biological Process	GO:0006481	C-terminal protein methylation	IBA	J:265628
Biological Process	GO:0006481	C-terminal protein methylation	IMP	J:62754
Biological Process	GO:0008340	determination of adult lifespan	IGI	J:199185
Biological Process	GO:0048144	fibroblast proliferation	IMP	J:88170
Biological Process	GO:0001701	in utero embryonic development	IMP	J:67598
Biological Process	GO:0001701	in utero embryonic development	IMP	J:77742
Biological Process	GO:0001889	liver development	IMP	J:77742
Biological Process	GO:0032259	methylation	IEA	J:60000
Biological Process	GO:0035264	multicellular organism growth	IGI	J:199185
Biological Process	GO:0035264	multicellular organism growth	IMP	J:67598
Biological Process	GO:0050905	neuromuscular process	IGI	J:199185
Biological Process	GO:0048146	positive regulation of fibroblast proliferation	IMP	J:88170
Biological Process	GO:0008104	protein localization	IMP	J:62754
Biological Process	GO:0006479	protein methylation	IMP	J:67598
Biological Process	GO:2000772	regulation of cellular senescence	IGI	J:199185
Biological Process	GO:0032880	regulation of protein localization	IMP	J:199185
Biological Process	GO:0046578	regulation of Ras protein signal transduction	IGI	J:88170
Biological Process	GO:0046498	S-adenosylhomocysteine metabolic process	ISO	J:155856
Biological Process	GO:0046499	S-adenosylmethioninamine metabolic process	ISO	J:155856
Biological Process	GO:0031929	TOR signaling	IMP	J:199185