GO Annotations Graph

• Symbol: P3h1
• Name: prolyl 3-hydroxylase 1
• ID: MGI:1888921

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0051213	dioxygenase activity	IEA	J:60000
Molecular Function	GO:0005506	iron ion binding	IEA	J:72247
Molecular Function	GO:0031418	L-ascorbic acid binding	IEA	J:60000
Molecular Function	GO:0031418	L-ascorbic acid binding	IEA	J:72247
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:60000
Molecular Function	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	IEA	J:72247
Molecular Function	GO:0019797	procollagen-proline 3-dioxygenase activity	IBA	J:265628
Molecular Function	GO:0019797	procollagen-proline 3-dioxygenase activity	ISO	J:154160
Cellular Component	GO:0005604	basement membrane	ISO	J:73065
Cellular Component	GO:0005737	cytoplasm	ISO	J:63828
Cellular Component	GO:0005737	cytoplasm	ISO	J:63828
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	IBA	J:265628
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:154160
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005634	nucleus	ISO	J:63828
Cellular Component	GO:0005886	plasma membrane	TAS	J:63828
Biological Process	GO:0060348	bone development	ISO	J:164563
Biological Process	GO:0030199	collagen fibril organization	IMP	J:163884
Biological Process	GO:0030199	collagen fibril organization	IMP	J:163884
Biological Process	GO:0032963	collagen metabolic process	IBA	J:265628
Biological Process	GO:0032963	collagen metabolic process	ISO	J:154160
Biological Process	GO:0030308	negative regulation of cell growth	IDA	J:63828
Biological Process	GO:1901874	negative regulation of post-translational protein modification	ISO	J:164563
Biological Process	GO:0010976	positive regulation of neuron projection development	ISO	J:155856
Biological Process	GO:0006457	protein folding	ISO	J:164563
Biological Process	GO:0018126	protein hydroxylation	ISO	J:164563
Biological Process	GO:0050821	protein stabilization	ISO	J:164563
Biological Process	GO:0030278	regulation of ossification	IMP	J:163884
Biological Process	GO:0050708	regulation of protein secretion	ISO	J:164563