GO Annotations Graph

• Symbol: Fmnl1
• Name: formin-like 1
• ID: MGI:1888994

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003779	actin binding	IEA	J:72247
Molecular Function	GO:0051015	actin filament binding	IDA	J:184956
Molecular Function	GO:0051015	actin filament binding	IBA	J:265628
Molecular Function	GO:0032794	GTPase activating protein binding	IDA	J:184956
Molecular Function	GO:0032794	GTPase activating protein binding	ISO	J:164563
Molecular Function	GO:0005522	profilin binding	IDA	J:64031
Molecular Function	GO:0005515	protein binding	IPI	J:314093
Molecular Function	GO:0031267	small GTPase binding	IDA	J:184956
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	IDA	J:184956
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-5663241
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-5665656
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-5665684
Cellular Component	GO:0005829	cytosol	IBA	J:265628
Cellular Component	GO:0005829	cytosol	IDA	J:64031
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0045335	phagocytic vesicle	IDA	J:184956
Cellular Component	GO:0005886	plasma membrane	IDA	J:184956
Biological Process	GO:0030036	actin cytoskeleton organization	IEA	J:72247
Biological Process	GO:0051014	actin filament severing	IDA	J:184956
Biological Process	GO:0016477	cell migration	IBA	J:265628
Biological Process	GO:0016043	cellular component organization	IEA	J:72247
Biological Process	GO:0030866	cortical actin cytoskeleton organization	ISO	J:164563
Biological Process	GO:0030866	cortical actin cytoskeleton organization	IBA	J:265628
Biological Process	GO:0007010	cytoskeleton organization	IEA	J:72247
Biological Process	GO:0022604	regulation of cell morphogenesis	IEA	J:72247
Biological Process	GO:0008360	regulation of cell shape	ISO	J:164563
Biological Process	GO:0008360	regulation of cell shape	IBA	J:265628
Biological Process	GO:0006929	substrate-dependent cell migration	IMP	J:64031