GO Annotations Graph

• Symbol: Angptl4
• Name: angiopoietin-like 4
• ID: MGI:1888999

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0004857	enzyme inhibitor activity	IDA	J:113960
Molecular Function	GO:0004857	enzyme inhibitor activity	IBA	J:265628
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Cellular Component	GO:0062023	collagen-containing extracellular matrix	IBA	J:265628
Cellular Component	GO:0005576	extracellular region	ISO	J:164563
Cellular Component	GO:0005576	extracellular region	IDA	J:61082
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Cellular Component	GO:0005615	extracellular space	IDA	J:62998
Cellular Component	GO:0005615	extracellular space	ISO	J:61082
Biological Process	GO:0001525	angiogenesis	IEA	J:72247
Biological Process	GO:0001525	angiogenesis	IEA	J:60000
Biological Process	GO:0009267	cellular response to starvation	NAS	J:64473
Biological Process	GO:0072577	endothelial cell apoptotic process	IDA	J:61082
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0043066	negative regulation of apoptotic process	IDA	J:61082
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:164563
Biological Process	GO:2000352	negative regulation of endothelial cell apoptotic process	IDA	J:61082
Biological Process	GO:0051005	negative regulation of lipoprotein lipase activity	IDA	J:113960
Biological Process	GO:0051005	negative regulation of lipoprotein lipase activity	ISO	J:164563
Biological Process	GO:0045834	positive regulation of lipid metabolic process	NAS	J:113960
Biological Process	GO:0043335	protein unfolding	ISO	J:164563
Biological Process	GO:0070328	triglyceride homeostasis	IMP	J:155061
Biological Process	GO:0070328	triglyceride homeostasis	IBA	J:265628