GO Annotations Graph

• Symbol: Rangrf
• Name: RAN guanine nucleotide release factor
• ID: MGI:1889073

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	IBA	J:265628
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	IDA	J:63595
Molecular Function	GO:0031267	small GTPase binding	ISO	J:164563
Molecular Function	GO:0031267	small GTPase binding	IBA	J:265628
Molecular Function	GO:0031267	small GTPase binding	IDA	J:63595
Molecular Function	GO:0017080	sodium channel regulator activity	IMP	J:200449
Molecular Function	GO:0017080	sodium channel regulator activity	ISO	J:164563
Molecular Function	GO:0017080	sodium channel regulator activity	IBA	J:265628
Molecular Function	GO:0044325	transmembrane transporter binding	IPI	J:184959
Molecular Function	GO:0044325	transmembrane transporter binding	ISO	J:164563
Molecular Function	GO:0044325	transmembrane transporter binding	IBA	J:265628
Cellular Component	GO:0005901	caveola	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0014704	intercalated disc	IDA	J:184959
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	IDA	J:63595
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Cellular Component	GO:0005791	rough endoplasmic reticulum	ISO	J:164563
Biological Process	GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	ISO	J:164563
Biological Process	GO:0060047	heart contraction	IBA	J:265628
Biological Process	GO:0006913	nucleocytoplasmic transport	TAS	J:63595
Biological Process	GO:2000010	positive regulation of protein localization to cell surface	ISO	J:164563
Biological Process	GO:1903078	positive regulation of protein localization to plasma membrane	ISO	J:164563
Biological Process	GO:0032527	protein exit from endoplasmic reticulum	ISO	J:164563
Biological Process	GO:0006606	protein import into nucleus	IBA	J:265628
Biological Process	GO:0015031	protein transport	IEA	J:60000
Biological Process	GO:0098905	regulation of bundle of His cell action potential	ISO	J:164563
Biological Process	GO:0098909	regulation of cardiac muscle cell action potential involved in regulation of contraction	ISO	J:164563
Biological Process	GO:0003254	regulation of membrane depolarization	IMP	J:200449
Biological Process	GO:0003254	regulation of membrane depolarization	ISO	J:164563
Biological Process	GO:0003254	regulation of membrane depolarization	IBA	J:265628
Biological Process	GO:1900825	regulation of membrane depolarization during cardiac muscle cell action potential	ISO	J:164563
Biological Process	GO:0042391	regulation of membrane potential	ISO	J:164563
Biological Process	GO:0090226	regulation of microtubule nucleation by Ran protein signal transduction	ISO	J:164563
Biological Process	GO:1902305	regulation of sodium ion transmembrane transport	ISO	J:164563
Biological Process	GO:1902305	regulation of sodium ion transmembrane transport	IMP	J:200449
Biological Process	GO:2000649	regulation of sodium ion transmembrane transporter activity	ISO	J:164563
Biological Process	GO:2000649	regulation of sodium ion transmembrane transporter activity	IMP	J:200449
Biological Process	GO:2000649	regulation of sodium ion transmembrane transporter activity	IBA	J:265628