GO Annotations Graph

• Symbol: Akirin2
• Name: akirin 2
• ID: MGI:1889364

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0019899	enzyme binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0140677	molecular function activator activity	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:216064
Molecular Function	GO:0030674	protein-macromolecule adaptor activity	ISO	J:164563
Molecular Function	GO:0030674	protein-macromolecule adaptor activity	IDA	J:216064
Molecular Function	GO:0003712	transcription coregulator activity	IBA	J:265628
Cellular Component	GO:0000785	chromatin	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IDA	J:275243
Cellular Component	GO:0016020	membrane	IDA	J:275243
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:275243
Cellular Component	GO:0005634	nucleus	IDA	J:216064
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	ISO	J:130487
Cellular Component	GO:0017053	transcription repressor complex	ISO	J:155856
Biological Process	GO:0002250	adaptive immune response	IEA	J:60000
Biological Process	GO:0021987	cerebral cortex development	IMP	J:237195
Biological Process	GO:0042742	defense response to bacterium	IMP	J:216064
Biological Process	GO:0009792	embryo development ending in birth or egg hatching	IMP	J:130487
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0045087	innate immune response	IEA	J:60000
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:155856
Biological Process	GO:0010629	negative regulation of gene expression	ISO	J:155856
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:155856
Biological Process	GO:0071630	nuclear protein quality control by the ubiquitin-proteasome system	ISO	J:164563
Biological Process	GO:0002821	positive regulation of adaptive immune response	IMP	J:322367
Biological Process	GO:0050871	positive regulation of B cell activation	IMP	J:322367
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:155856
Biological Process	GO:0010950	positive regulation of endopeptidase activity	ISO	J:155856
Biological Process	GO:0045089	positive regulation of innate immune response	IMP	J:216064
Biological Process	GO:0045089	positive regulation of innate immune response	IBA	J:265628
Biological Process	GO:0032755	positive regulation of interleukin-6 production	IDA	J:216064
Biological Process	GO:0032755	positive regulation of interleukin-6 production	IMP	J:130487
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:216064
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:130487
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:130487
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:130487
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:130487
Biological Process	GO:0031144	proteasome localization	ISO	J:164563
Biological Process	GO:0006606	protein import into nucleus	ISO	J:164563
Biological Process	GO:0015031	protein transport	IEA	J:60000
Biological Process	GO:0051147	regulation of muscle cell differentiation	IMP	J:275243
Biological Process	GO:0032496	response to lipopolysaccharide	IMP	J:130487