GO Annotations Graph

• Symbol: Pidd1
• Name: p53 induced death domain protein 1
• ID: MGI:1889507

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0004175	endopeptidase activity	ISO	J:164563
Molecular Function	GO:0004175	endopeptidase activity	IBA	J:265628
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:101402
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IDA	J:101402
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:1905369	endopeptidase complex	ISO	J:164563
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:0005730	nucleolus	NAS	J:246097
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Biological Process	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	ISO	J:164563
Biological Process	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	IBA	J:265628
Biological Process	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	IGI	J:101402
Biological Process	GO:0006915	apoptotic process	ISO	J:164563
Biological Process	GO:0097190	apoptotic signaling pathway	IGI	J:101402
Biological Process	GO:0097190	apoptotic signaling pathway	IGI	J:101402
Biological Process	GO:0097190	apoptotic signaling pathway	IGI	J:101402
Biological Process	GO:0006974	DNA damage response	ISO	J:164563
Biological Process	GO:0006974	DNA damage response	NAS	J:320335
Biological Process	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	ISO	J:164563
Biological Process	GO:0097191	extrinsic apoptotic signaling pathway	IGI	J:101402
Biological Process	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	IGI	J:101402
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0043065	positive regulation of apoptotic process	NAS	J:320335
Biological Process	GO:0016540	protein autoprocessing	ISO	J:164563
Biological Process	GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling	ISO	J:164563
Biological Process	GO:0007165	signal transduction	IBA	J:265628