GO Annotations Graph

• Symbol: Robo2
• Name: roundabout guidance receptor 2
• ID: MGI:1890110

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008046	axon guidance receptor activity	ISO	J:155856
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Cellular Component	GO:0030673	axolemma	IDA	J:89438
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0043005	neuron projection	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-9010527
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-9010658
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-9010660
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-9010662
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-9010668
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-9014847
Biological Process	GO:0035904	aorta development	IGI	J:244269
Biological Process	GO:0003180	aortic valve morphogenesis	IGI	J:244269
Biological Process	GO:0007411	axon guidance	ISO	J:155856
Biological Process	GO:0007411	axon guidance	IMP	J:89780
Biological Process	GO:0016199	axon midline choice point recognition	IGI	J:143208
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0006935	chemotaxis	IEA	J:60000
Biological Process	GO:0003272	endocardial cushion formation	IGI	J:244269
Biological Process	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules	ISO	J:164563
Biological Process	GO:0001656	metanephros development	IMP	J:90324
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0050925	negative regulation of negative chemotaxis	ISO	J:164563
Biological Process	GO:0007399	nervous system development	IEA	J:60000
Biological Process	GO:0021891	olfactory bulb interneuron development	IMP	J:119469
Biological Process	GO:0003148	outflow tract septum morphogenesis	IGI	J:244269
Biological Process	GO:0050772	positive regulation of axonogenesis	ISO	J:164563
Biological Process	GO:0035481	positive regulation of Notch signaling pathway involved in heart induction	IDA	J:244269
Biological Process	GO:0003184	pulmonary valve morphogenesis	IGI	J:244269
Biological Process	GO:0031290	retinal ganglion cell axon guidance	IMP	J:154456
Biological Process	GO:0001657	ureteric bud development	ISO	J:164563
Biological Process	GO:0001657	ureteric bud development	IMP	J:90324
Biological Process	GO:0060412	ventricular septum morphogenesis	IGI	J:244269