GO Annotations Graph

• Symbol: Erbin
• Name: Erbb2 interacting protein
• ID: MGI:1890169

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005176	ErbB-2 class receptor binding	IEA	J:72247
Molecular Function	GO:0005515	protein binding	IPI	J:63225
Molecular Function	GO:0005102	signaling receptor binding	ISO	J:164563
Molecular Function	GO:0005102	signaling receptor binding	IBA	J:265628
Cellular Component	GO:0016323	basolateral plasma membrane	ISO	J:164563
Cellular Component	GO:0016323	basolateral plasma membrane	IBA	J:265628
Cellular Component	GO:0016323	basolateral plasma membrane	IDA	J:63225
Cellular Component	GO:0030054	cell junction	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:197472
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:197472
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:197472
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:197472
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:197472
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:197472
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:197472
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:197472
Cellular Component	GO:0030056	hemidesmosome	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0031594	neuromuscular junction	ISO	J:155856
Cellular Component	GO:0016607	nuclear speck	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0098794	postsynapse	IDA	J:197472
Cellular Component	GO:0098794	postsynapse	IDA	J:197472
Cellular Component	GO:0098794	postsynapse	IDA	J:197472
Cellular Component	GO:0099572	postsynaptic specialization	ISO	J:155856
Biological Process	GO:0071356	cellular response to tumor necrosis factor	ISO	J:164563
Biological Process	GO:0071356	cellular response to tumor necrosis factor	IBA	J:265628
Biological Process	GO:0071638	negative regulation of monocyte chemotactic protein-1 production	IMP	J:221560
Biological Process	GO:0032088	negative regulation of NF-kappaB transcription factor activity	ISO	J:164563
Biological Process	GO:0032088	negative regulation of NF-kappaB transcription factor activity	IBA	J:265628
Biological Process	GO:0070433	negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	IMP	J:221560
Biological Process	GO:0070433	negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	ISO	J:164563
Biological Process	GO:0006605	protein targeting	IDA	J:63225
Biological Process	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	IDA	J:197472
Biological Process	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	IDA	J:197472
Biological Process	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	IDA	J:197472
Biological Process	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	IMP	J:197472
Biological Process	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	IDA	J:197472
Biological Process	GO:0032496	response to lipopolysaccharide	ISO	J:164563
Biological Process	GO:0032495	response to muramyl dipeptide	ISO	J:164563
Biological Process	GO:0007165	signal transduction	IEA	J:72247