GO Annotations Graph

• Symbol: Mcoln1
• Name: mucolipin 1
• ID: MGI:1890498

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0097682	intracellular phosphatidylinositol-3,5-bisphosphate-sensitive monatomic cation channel activity	IDA	J:250436
Molecular Function	GO:0099604	ligand-gated calcium channel activity	ISO	J:164563
Molecular Function	GO:0008289	lipid binding	IEA	J:60000
Molecular Function	GO:0005261	monoatomic cation channel activity	ISO	J:75410
Molecular Function	GO:0072345	NAADP-sensitive calcium-release channel activity	ISO	J:155856
Molecular Function	GO:0072345	NAADP-sensitive calcium-release channel activity	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:240995
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0005768	endosome	IEA	J:60000
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0097708	intracellular vesicle	EXP	J:240995
Cellular Component	GO:0005770	late endosome	ISO	J:164563
Cellular Component	GO:0005770	late endosome	ISO	J:75410
Cellular Component	GO:0005765	lysosomal membrane	ISO	J:155856
Cellular Component	GO:0005765	lysosomal membrane	ISO	J:164563
Cellular Component	GO:0005765	lysosomal membrane	IBA	J:265628
Cellular Component	GO:0005764	lysosome	ISO	J:164563
Cellular Component	GO:0016020	membrane	IDA	J:250436
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0016020	membrane	ISO	J:75410
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0043235	receptor complex	ISO	J:194542
Biological Process	GO:0002250	adaptive immune response	IEA	J:60000
Biological Process	GO:0097352	autophagosome maturation	IMP	J:165988
Biological Process	GO:1901660	calcium ion export	ISO	J:164563
Biological Process	GO:0070588	calcium ion transmembrane transport	ISO	J:164563
Biological Process	GO:0006816	calcium ion transport	IEA	J:60000
Biological Process	GO:0071277	cellular response to calcium ion	IMP	J:250436
Biological Process	GO:0071467	cellular response to pH	IMP	J:250436
Biological Process	GO:0016197	endosomal transport	ISO	J:75410
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0098655	monoatomic cation transmembrane transport	IDA	J:250436
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0090382	phagosome maturation	ISO	J:164563
Biological Process	GO:0090382	phagosome maturation	IDA	J:289081
Biological Process	GO:1905673	positive regulation of lysosome organization	ISO	J:164563
Biological Process	GO:0051289	protein homotetramerization	ISO	J:164563
Biological Process	GO:0051289	protein homotetramerization	IDA	J:250436
Biological Process	GO:0051209	release of sequestered calcium ion into cytosol	ISO	J:155856