GO Annotations Graph

• Symbol: Lin28a
• Name: lin-28 homolog A
• ID: MGI:1890546

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0002151	G-quadruplex RNA binding	IDA	J:235236
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0035198	miRNA binding	IDA	J:235236
Molecular Function	GO:0035198	miRNA binding	IDA	J:262365
Molecular Function	GO:0035198	miRNA binding	IDA	J:152654
Molecular Function	GO:0035198	miRNA binding	IDA	J:152654
Molecular Function	GO:0003729	mRNA binding	IDA	J:121228
Molecular Function	GO:0003676	nucleic acid binding	IEA	J:72247
Molecular Function	GO:1905538	polysome binding	ISO	J:164563
Molecular Function	GO:0070883	pre-miRNA binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:197683
Molecular Function	GO:0005515	protein binding	IPI	J:262365
Molecular Function	GO:0140517	protein-RNA adaptor activity	ISO	J:164563
Molecular Function	GO:0003723	RNA binding	IDA	J:235254
Molecular Function	GO:0003723	RNA binding	ISO	J:164563
Molecular Function	GO:0003723	RNA binding	IDA	J:152654
Molecular Function	GO:0003723	RNA binding	IDA	J:152656
Molecular Function	GO:1990825	sequence-specific mRNA binding	IDA	J:235236
Molecular Function	GO:0031369	translation initiation factor binding	IPI	J:121228
Molecular Function	GO:0008270	zinc ion binding	IEA	J:72247
Cellular Component	GO:0005737	cytoplasm	IDA	J:121228
Cellular Component	GO:0005737	cytoplasm	ISO	J:152654
Cellular Component	GO:0005737	cytoplasm	ISO	J:156954
Cellular Component	GO:0005737	cytoplasm	IDA	J:83937
Cellular Component	GO:0005737	cytoplasm	IDA	J:152654
Cellular Component	GO:0010494	cytoplasmic stress granule	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	IEA	J:60000
Cellular Component	GO:0005730	nucleolus	ISO	J:164563
Cellular Component	GO:0005730	nucleolus	IDA	J:121228
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0000932	P-body	ISO	J:164563
Cellular Component	GO:0005844	polysome	ISO	J:164563
Cellular Component	GO:1990904	ribonucleoprotein complex	ISO	J:164563
Cellular Component	GO:0005791	rough endoplasmic reticulum	IDA	J:235254
Biological Process	GO:0071333	cellular response to glucose stimulus	IMP	J:177113
Biological Process	GO:0007281	germ cell development	IMP	J:151610
Biological Process	GO:0007281	germ cell development	IGI	J:151610
Biological Process	GO:0010587	miRNA catabolic process	IMP	J:152654
Biological Process	GO:0010587	miRNA catabolic process	IMP	J:152656
Biological Process	GO:0010587	miRNA catabolic process	ISO	J:164563
Biological Process	GO:0010587	miRNA catabolic process	IDA	J:177113
Biological Process	GO:0010586	miRNA metabolic process	IDA	J:159026
Biological Process	GO:0045686	negative regulation of glial cell differentiation	IDA	J:159026
Biological Process	GO:2000632	negative regulation of pre-miRNA processing	ISO	J:164563
Biological Process	GO:0017148	negative regulation of translation	IDA	J:235254
Biological Process	GO:1901724	positive regulation of cell proliferation involved in kidney development	IMP	J:211179
Biological Process	GO:2000767	positive regulation of cytoplasmic translation	ISO	J:164563
Biological Process	GO:0045666	positive regulation of neuron differentiation	IDA	J:159026
Biological Process	GO:0051897	positive regulation of protein kinase B signaling	IDA	J:177113
Biological Process	GO:0032008	positive regulation of TOR signaling	IDA	J:177113
Biological Process	GO:0045727	positive regulation of translation	IDA	J:121228
Biological Process	GO:0031054	pre-miRNA processing	IMP	J:152654
Biological Process	GO:0031054	pre-miRNA processing	ISO	J:164563
Biological Process	GO:0031054	pre-miRNA processing	IMP	J:152656
Biological Process	GO:0031054	pre-miRNA processing	IDA	J:152654
Biological Process	GO:0060964	regulation of miRNA-mediated gene silencing	IGI	J:158290
Biological Process	GO:0071076	RNA 3' uridylation	IDA	J:281190
Biological Process	GO:0031123	RNA 3'-end processing	ISO	J:164563
Biological Process	GO:0031047	RNA-mediated gene silencing	IEA	J:60000
Biological Process	GO:0048863	stem cell differentiation	IMP	J:152656
Biological Process	GO:0048863	stem cell differentiation	IMP	J:152654
Biological Process	GO:0019827	stem cell population maintenance	ISO	J:164563