GO Annotations Graph

• Symbol: Sptbn4
• Name: spectrin beta, non-erythrocytic 4
• ID: MGI:1890574

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003779	actin binding	IDA	J:165334
Molecular Function	GO:0051015	actin filament binding	IBA	J:265628
Molecular Function	GO:0030506	ankyrin binding	IDA	J:77228
Molecular Function	GO:0030506	ankyrin binding	ISO	J:164563
Molecular Function	GO:0030506	ankyrin binding	ISS	J:63322
Molecular Function	GO:0019902	phosphatase binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:240720
Molecular Function	GO:0005515	protein binding	IPI	J:165334
Molecular Function	GO:0005515	protein binding	IPI	J:165334
Molecular Function	GO:0030507	spectrin binding	IDA	J:165334
Cellular Component	GO:0005884	actin filament	IDA	J:77228
Cellular Component	GO:0005912	adherens junction	IDA	J:77228
Cellular Component	GO:0030424	axon	ISO	J:155856
Cellular Component	GO:0030424	axon	IDA	J:93411
Cellular Component	GO:0043203	axon hillock	IDA	J:93411
Cellular Component	GO:0043194	axon initial segment	IDA	J:240366
Cellular Component	GO:0043194	axon initial segment	IDA	J:77228
Cellular Component	GO:0043194	axon initial segment	ISO	J:155856
Cellular Component	GO:0043194	axon initial segment	IDA	J:165334
Cellular Component	GO:0043194	axon initial segment	IDA	J:228724
Cellular Component	GO:0070852	cell body fiber	IDA	J:142574
Cellular Component	GO:0030054	cell junction	IBA	J:265628
Cellular Component	GO:0042995	cell projection	IBA	J:265628
Cellular Component	GO:0030864	cortical actin cytoskeleton	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISS	J:63322
Cellular Component	GO:0014704	intercalated disc	IDA	J:239053
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0043025	neuronal cell body	IDA	J:165334
Cellular Component	GO:0033268	node of Ranvier	ISO	J:155856
Cellular Component	GO:0033268	node of Ranvier	IDA	J:77228
Cellular Component	GO:0033268	node of Ranvier	IMP	J:108683
Cellular Component	GO:0016363	nuclear matrix	ISO	J:164563
Cellular Component	GO:0016363	nuclear matrix	ISS	J:63322
Cellular Component	GO:0033270	paranode region of axon	IDA	J:166099
Cellular Component	GO:0005886	plasma membrane	IDA	J:77228
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0016605	PML body	ISS	J:63322
Cellular Component	GO:0016605	PML body	ISO	J:164563
Cellular Component	GO:0008091	spectrin	ISO	J:164563
Cellular Component	GO:0008091	spectrin	ISS	J:69428
Biological Process	GO:0030036	actin cytoskeleton organization	IBA	J:265628
Biological Process	GO:0030534	adult behavior	IMP	J:120916
Biological Process	GO:0030534	adult behavior	IMP	J:11718
Biological Process	GO:0007628	adult walking behavior	IMP	J:11718
Biological Process	GO:0007409	axonogenesis	IMP	J:11718
Biological Process	GO:0061337	cardiac conduction	IMP	J:165334
Biological Process	GO:0021952	central nervous system projection neuron axonogenesis	IBA	J:265628
Biological Process	GO:0021952	central nervous system projection neuron axonogenesis	IMP	J:120916
Biological Process	GO:0045162	clustering of voltage-gated sodium channels	IMP	J:77228
Biological Process	GO:0045162	clustering of voltage-gated sodium channels	IMP	J:120916
Biological Process	GO:0009566	fertilization	IMP	J:11718
Biological Process	GO:0010459	negative regulation of heart rate	IMP	J:165334
Biological Process	GO:0040018	positive regulation of multicellular organism growth	IMP	J:11718
Biological Process	GO:0008104	protein localization	IMP	J:108683
Biological Process	GO:0008104	protein localization	IMP	J:165334
Biological Process	GO:0072659	protein localization to plasma membrane	IMP	J:77228
Biological Process	GO:0033135	regulation of peptidyl-serine phosphorylation	IDA	J:165334
Biological Process	GO:0002028	regulation of sodium ion transport	IMP	J:165334
Biological Process	GO:0022414	reproductive process	IMP	J:120916
Biological Process	GO:0007605	sensory perception of sound	IMP	J:93411
Biological Process	GO:0019226	transmission of nerve impulse	IMP	J:93411