GO Annotations Graph

• Symbol: Npm2
• Name: nucleophosmin/nucleoplasmin 2
• ID: MGI:1890811

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IBA	J:265628
Molecular Function	GO:0003682	chromatin binding	IDA	J:202816
Molecular Function	GO:0019899	enzyme binding	ISO	J:155856
Molecular Function	GO:0042393	histone binding	IBA	J:265628
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0003723	RNA binding	IBA	J:265628
Cellular Component	GO:0000785	chromatin	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005730	nucleolus	IBA	J:265628
Cellular Component	GO:0005654	nucleoplasm	IBA	J:265628
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:83658
Biological Process	GO:0001824	blastocyst development	ISO	J:164563
Biological Process	GO:0006325	chromatin organization	IEA	J:60000
Biological Process	GO:0006338	chromatin remodeling	ISO	J:164563
Biological Process	GO:0006338	chromatin remodeling	IBA	J:265628
Biological Process	GO:0006338	chromatin remodeling	IMP	J:83658
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0043085	positive regulation of catalytic activity	ISO	J:155856
Biological Process	GO:0051054	positive regulation of DNA metabolic process	ISO	J:155856
Biological Process	GO:0045740	positive regulation of DNA replication	ISO	J:155856
Biological Process	GO:0045740	positive regulation of DNA replication	IBA	J:265628
Biological Process	GO:0045836	positive regulation of meiotic nuclear division	ISO	J:164563
Biological Process	GO:0007096	regulation of exit from mitosis	ISO	J:164563
Biological Process	GO:0007338	single fertilization	ISO	J:164563