GO Annotations Graph

• Symbol: Lrat
• Name: lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase)
• ID: MGI:1891259

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0016746	acyltransferase activity	IEA	J:60000
Molecular Function	GO:0102279	lecithin:11-cis retinol acyltransferase activity	IEA	J:72245
Molecular Function	GO:0008374	O-acyltransferase activity	IDA	J:66429
Molecular Function	GO:0047173	phosphatidylcholine-retinol O-acyltransferase activity	IMP	J:287029
Molecular Function	GO:0047173	phosphatidylcholine-retinol O-acyltransferase activity	ISO	J:155856
Molecular Function	GO:0047173	phosphatidylcholine-retinol O-acyltransferase activity	ISO	J:164563
Molecular Function	GO:0047173	phosphatidylcholine-retinol O-acyltransferase activity	IBA	J:265628
Molecular Function	GO:0001972	retinoic acid binding	ISO	J:155856
Molecular Function	GO:0019841	retinol binding	ISO	J:155856
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:287029
Cellular Component	GO:0005768	endosome	IEA	J:60000
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:155856
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005771	multivesicular body	ISO	J:155856
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:155856
Cellular Component	GO:0005791	rough endoplasmic reticulum	ISO	J:155856
Cellular Component	GO:0005791	rough endoplasmic reticulum	IBA	J:265628
Biological Process	GO:0006653	1,2-diacyl-sn-glycero-3-phosphocholine metabolic process	TAS	J:66429
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	IEP	J:163558
Biological Process	GO:0009790	embryo development	IGI	J:132367
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0032370	positive regulation of lipid transport	IGI	J:210500
Biological Process	GO:0032370	positive regulation of lipid transport	IGI	J:210500
Biological Process	GO:0009617	response to bacterium	IEP	J:190322
Biological Process	GO:0050896	response to stimulus	IEA	J:60000
Biological Process	GO:0042572	retinol metabolic process	ISO	J:155856
Biological Process	GO:0042572	retinol metabolic process	ISO	J:164563
Biological Process	GO:0042572	retinol metabolic process	IMP	J:287029
Biological Process	GO:0042572	retinol metabolic process	IBA	J:265628
Biological Process	GO:0042572	retinol metabolic process	IMP	J:132367
Biological Process	GO:0042572	retinol metabolic process	IGI	J:132367
Biological Process	GO:0007601	visual perception	IEA	J:60000
Biological Process	GO:0006776	vitamin A metabolic process	ISO	J:155856
Biological Process	GO:0006776	vitamin A metabolic process	IMP	J:287029
Biological Process	GO:0006776	vitamin A metabolic process	IBA	J:265628
Biological Process	GO:0006776	vitamin A metabolic process	IDA	J:66429