GO Annotations Graph

• Symbol: Lpin1
• Name: lipin 1
• ID: MGI:1891340

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0042826	histone deacetylase binding	IDA	J:162572
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0042975	peroxisome proliferator activated receptor binding	IPI	J:129744
Molecular Function	GO:0008195	phosphatidate phosphatase activity	ISO	J:164563
Molecular Function	GO:0008195	phosphatidate phosphatase activity	ISO	J:164563
Molecular Function	GO:0008195	phosphatidate phosphatase activity	IDA	J:169933
Molecular Function	GO:0008195	phosphatidate phosphatase activity	IBA	J:265628
Molecular Function	GO:0008195	phosphatidate phosphatase activity	IDA	J:120935
Molecular Function	GO:0005515	protein binding	IPI	J:159054
Molecular Function	GO:0005515	protein binding	IPI	J:129744
Molecular Function	GO:0005515	protein binding	IPI	J:162572
Molecular Function	GO:0005515	protein binding	IPI	J:162572
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	IDA	J:162572
Molecular Function	GO:0003713	transcription coactivator activity	IDA	J:129744
Molecular Function	GO:0003713	transcription coactivator activity	IDA	J:159054
Molecular Function	GO:0003713	transcription coactivator activity	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IDA	J:159054
Cellular Component	GO:0005737	cytoplasm	IDA	J:180810
Cellular Component	GO:0005737	cytoplasm	IDA	J:169933
Cellular Component	GO:0005737	cytoplasm	IDA	J:281194
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:281194
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005741	mitochondrial outer membrane	IDA	J:169933
Cellular Component	GO:0005741	mitochondrial outer membrane	IBA	J:265628
Cellular Component	GO:0005739	mitochondrion	IEA	J:60000
Cellular Component	GO:0031965	nuclear membrane	IDA	J:180810
Cellular Component	GO:0005634	nucleus	IDA	J:281194
Cellular Component	GO:0005634	nucleus	IDA	J:159054
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:66739
Cellular Component	GO:0005634	nucleus	IDA	J:162572
Cellular Component	GO:0005667	transcription regulator complex	IDA	J:162572
Biological Process	GO:0030036	actin cytoskeleton organization	IMP	J:42314
Biological Process	GO:0044255	cellular lipid metabolic process	IMP	J:181551
Biological Process	GO:0032869	cellular response to insulin stimulus	ISO	J:155856
Biological Process	GO:0032869	cellular response to insulin stimulus	IBA	J:265628
Biological Process	GO:0032869	cellular response to insulin stimulus	IMP	J:42314
Biological Process	GO:0045444	fat cell differentiation	NAS	J:66739
Biological Process	GO:0009062	fatty acid catabolic process	IDA	J:129744
Biological Process	GO:0009062	fatty acid catabolic process	IBA	J:265628
Biological Process	GO:0006955	immune response	IMP	J:181551
Biological Process	GO:0006629	lipid metabolic process	IMP	J:9801
Biological Process	GO:0006629	lipid metabolic process	IMP	J:90859
Biological Process	GO:0000266	mitochondrial fission	IDA	J:169933
Biological Process	GO:0031642	negative regulation of myelination	ISO	J:155856
Biological Process	GO:1903741	negative regulation of phosphatidate phosphatase activity	ISO	J:155856
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IGI	J:162572
Biological Process	GO:0046473	phosphatidic acid metabolic process	ISO	J:164563
Biological Process	GO:0120162	positive regulation of cold-induced thermogenesis	IMP	J:192733
Biological Process	GO:0045740	positive regulation of DNA replication	ISO	J:155856
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:129744
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:162572
Biological Process	GO:0045598	regulation of fat cell differentiation	IMP	J:66739
Biological Process	GO:0045598	regulation of fat cell differentiation	IMP	J:66739
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IEA	J:72247
Biological Process	GO:0031529	ruffle organization	IMP	J:42314
Biological Process	GO:0019432	triglyceride biosynthetic process	ISO	J:164563
Biological Process	GO:0019432	triglyceride biosynthetic process	IBA	J:265628
Biological Process	GO:0006642	triglyceride mobilization	IDA	J:129744