GO Annotations Graph

• Symbol: Gps2
• Name: G protein pathway suppressor 2
• ID: MGI:1891751

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0030332	cyclin binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:259118
Molecular Function	GO:0005515	protein binding	IPI	J:135288
Molecular Function	GO:0003713	transcription coactivator activity	IDA	J:259114
Molecular Function	GO:0003713	transcription coactivator activity	IDA	J:259113
Molecular Function	GO:0003713	transcription coactivator activity	ISO	J:164563
Molecular Function	GO:0003712	transcription coregulator activity	IBA	J:265628
Molecular Function	GO:0003714	transcription corepressor activity	ISO	J:164563
Molecular Function	GO:0003714	transcription corepressor activity	IDA	J:219351
Cellular Component	GO:0005737	cytoplasm	IDA	J:259118
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	IDA	J:259114
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-NUL-9005747
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-NUL-9005752
Cellular Component	GO:0005634	nucleus	IDA	J:259114
Cellular Component	GO:0005634	nucleus	IDA	J:243390
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:259118
Cellular Component	GO:0005634	nucleus	IDA	J:224604
Cellular Component	GO:0005634	nucleus	IDA	J:135288
Cellular Component	GO:0005667	transcription regulator complex	IBA	J:265628
Cellular Component	GO:0017053	transcription repressor complex	IDA	J:219351
Cellular Component	GO:0017053	transcription repressor complex	ISO	J:164563
Biological Process	GO:0030183	B cell differentiation	IMP	J:240887
Biological Process	GO:0050859	negative regulation of B cell receptor signaling pathway	IMP	J:240887
Biological Process	GO:0045599	negative regulation of fat cell differentiation	IMP	J:243390
Biological Process	GO:0050728	negative regulation of inflammatory response	IDA	J:259118
Biological Process	GO:0046329	negative regulation of JNK cascade	IMP	J:259118
Biological Process	GO:0046329	negative regulation of JNK cascade	ISO	J:164563
Biological Process	GO:1900045	negative regulation of protein K63-linked ubiquitination	IDA	J:259114
Biological Process	GO:1900045	negative regulation of protein K63-linked ubiquitination	IMP	J:240887
Biological Process	GO:1900045	negative regulation of protein K63-linked ubiquitination	IDA	J:259118
Biological Process	GO:1900045	negative regulation of protein K63-linked ubiquitination	IDA	J:259113
Biological Process	GO:0034122	negative regulation of toll-like receptor signaling pathway	IMP	J:240887
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:219351
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway	IMP	J:259118
Biological Process	GO:0010875	positive regulation of cholesterol efflux	ISO	J:164563
Biological Process	GO:0035360	positive regulation of peroxisome proliferator activated receptor signaling pathway	IDA	J:259113
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:259113
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:259114
Biological Process	GO:0045598	regulation of fat cell differentiation	IDA	J:259113
Biological Process	GO:0019216	regulation of lipid metabolic process	IDA	J:259113
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0098780	response to mitochondrial depolarisation	IDA	J:259114