GO Annotations Graph

• Symbol: Becn1
• Name: beclin 1, autophagy related
• ID: MGI:1891828

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0051020	GTPase binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	IPI	J:240718
Molecular Function	GO:0043548	phosphatidylinositol 3-kinase binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:181308
Molecular Function	GO:0005515	protein binding	IPI	J:136548
Molecular Function	GO:0005515	protein binding	IPI	J:202483
Molecular Function	GO:0005515	protein binding	IPI	J:220500
Molecular Function	GO:0005515	protein binding	IPI	J:197027
Molecular Function	GO:0005515	protein binding	IPI	J:263555
Molecular Function	GO:0005515	protein binding	IPI	J:219056
Molecular Function	GO:0005515	protein binding	IPI	J:220512
Molecular Function	GO:0005515	protein binding	IPI	J:240718
Molecular Function	GO:0005515	protein binding	IPI	J:240718
Molecular Function	GO:0005515	protein binding	IPI	J:240718
Molecular Function	GO:0005515	protein binding	IPI	J:122795
Molecular Function	GO:0005515	protein binding	IPI	J:129990
Molecular Function	GO:0005515	protein binding	IPI	J:185616
Molecular Function	GO:0005515	protein binding	IPI	J:78719
Molecular Function	GO:0005515	protein binding	IPI	J:240718
Molecular Function	GO:0019901	protein kinase binding	ISO	J:164563
Molecular Function	GO:0030674	protein-macromolecule adaptor activity	ISO	J:164563
Molecular Function	GO:0031625	ubiquitin protein ligase binding	ISO	J:164563
Molecular Function	GO:0031625	ubiquitin protein ligase binding	ISO	J:155856
Cellular Component	GO:0005776	autophagosome	IDA	J:198700
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:122795
Cellular Component	GO:0032473	cytoplasmic side of mitochondrial outer membrane	ISO	J:164563
Cellular Component	GO:0031410	cytoplasmic vesicle	IDA	J:78719
Cellular Component	GO:0005856	cytoskeleton	ISS	J:64816
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005768	endosome	ISO	J:164563
Cellular Component	GO:0005794	Golgi apparatus	IEA	J:60000
Cellular Component	GO:0016020	membrane	ISS	J:64816
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0016604	nuclear body	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0045335	phagocytic vesicle	IDA	J:185616
Cellular Component	GO:0000407	phagophore assembly site	IBA	J:265628
Cellular Component	GO:0035032	phosphatidylinositol 3-kinase complex, class III	ISO	J:164563
Cellular Component	GO:0035032	phosphatidylinositol 3-kinase complex, class III	IDA	J:219056
Cellular Component	GO:0034271	phosphatidylinositol 3-kinase complex, class III, type I	IBA	J:265628
Cellular Component	GO:0034272	phosphatidylinositol 3-kinase complex, class III, type II	IBA	J:265628
Cellular Component	GO:0032991	protein-containing complex	IDA	J:129990
Cellular Component	GO:0005802	trans-Golgi network	ISO	J:155856
Cellular Component	GO:0005802	trans-Golgi network	IDA	J:78719
Biological Process	GO:0050435	amyloid-beta metabolic process	IMP	J:137727
Biological Process	GO:0001525	angiogenesis	TAS	J:215858
Biological Process	GO:0006915	apoptotic process	IEA	J:60000
Biological Process	GO:0000045	autophagosome assembly	IMP	J:219056
Biological Process	GO:0000045	autophagosome assembly	ISO	J:155856
Biological Process	GO:0000045	autophagosome assembly	IBA	J:265628
Biological Process	GO:0097352	autophagosome maturation	ISO	J:164563
Biological Process	GO:0006914	autophagy	IDA	J:197027
Biological Process	GO:0006914	autophagy	ISO	J:155856
Biological Process	GO:0006914	autophagy	ISO	J:164563
Biological Process	GO:0006914	autophagy	IDA	J:219054
Biological Process	GO:0006914	autophagy	IDA	J:122795
Biological Process	GO:0006914	autophagy	ISO	J:251260
Biological Process	GO:0006914	autophagy	IDA	J:78719
Biological Process	GO:0000422	autophagy of mitochondrion	ISO	J:164563
Biological Process	GO:0000422	autophagy of mitochondrion	IMP	J:136548
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0051301	cell division	IEA	J:60000
Biological Process	GO:0042149	cellular response to glucose starvation	IDA	J:219056
Biological Process	GO:0006995	cellular response to nitrogen starvation	IBA	J:265628
Biological Process	GO:0051607	defense response to virus	IEA	J:60000
Biological Process	GO:0045022	early endosome to late endosome transport	ISO	J:164563
Biological Process	GO:0006897	endocytosis	IEA	J:60000
Biological Process	GO:0006897	endocytosis	IEA	J:72247
Biological Process	GO:0043652	engulfment of apoptotic cell	IMP	J:219067
Biological Process	GO:0045324	late endosome to vacuole transport	IBA	J:265628
Biological Process	GO:0007040	lysosome organization	IMP	J:137727
Biological Process	GO:0016236	macroautophagy	IMP	J:219056
Biological Process	GO:0016236	macroautophagy	IGI	J:125097
Biological Process	GO:0016236	macroautophagy	IMP	J:86982
Biological Process	GO:0000423	mitophagy	ISO	J:164563
Biological Process	GO:0007080	mitotic metaphase plate congression	ISO	J:164563
Biological Process	GO:0043066	negative regulation of apoptotic process	IMP	J:136548
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:155856
Biological Process	GO:1902902	negative regulation of autophagosome assembly	IMP	J:240718
Biological Process	GO:0010507	negative regulation of autophagy	IMP	J:240718
Biological Process	GO:0060548	negative regulation of cell death	ISO	J:155856
Biological Process	GO:0008285	negative regulation of cell population proliferation	IDA	J:122795
Biological Process	GO:1905672	negative regulation of lysosome organization	ISO	J:155856
Biological Process	GO:0043069	negative regulation of programmed cell death	ISO	J:73065
Biological Process	GO:2000378	negative regulation of reactive oxygen species metabolic process	IMP	J:136548
Biological Process	GO:0048666	neuron development	IMP	J:137727
Biological Process	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process	ISO	J:164563
Biological Process	GO:1902425	positive regulation of attachment of mitotic spindle microtubules to kinetochore	ISO	J:164563
Biological Process	GO:2000786	positive regulation of autophagosome assembly	ISO	J:155856
Biological Process	GO:0010508	positive regulation of autophagy	ISO	J:155856
Biological Process	GO:0010508	positive regulation of autophagy	ISO	J:164563
Biological Process	GO:0010613	positive regulation of cardiac muscle hypertrophy	IMP	J:240718
Biological Process	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway	ISO	J:164563
Biological Process	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway	ISO	J:155856
Biological Process	GO:0006468	protein phosphorylation	ISO	J:164563
Biological Process	GO:0006622	protein targeting to lysosome	NAS	J:106494
Biological Process	GO:0065003	protein-containing complex assembly	ISO	J:164563
Biological Process	GO:0032801	receptor catabolic process	ISO	J:164563
Biological Process	GO:0010506	regulation of autophagy	ISO	J:164563
Biological Process	GO:0050790	regulation of catalytic activity	IMP	J:185616
Biological Process	GO:0032465	regulation of cytokinesis	ISO	J:164563
Biological Process	GO:0016241	regulation of macroautophagy	ISO	J:164563
Biological Process	GO:0098780	response to mitochondrial depolarisation	ISO	J:164563
Biological Process	GO:0051707	response to other organism	IDA	J:64816
Biological Process	GO:0061912	selective autophagy	ISO	J:164563