GO Annotations Graph

• Symbol: Nupr1
• Name: nuclear protein transcription regulator 1
• ID: MGI:1891834

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0010698	acetyltransferase activator activity	IMP	J:153063
Molecular Function	GO:0003682	chromatin binding	IDA	J:153063
Molecular Function	GO:0003677	DNA binding	ISO	J:164563
Molecular Function	GO:0060090	molecular adaptor activity	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:153063
Molecular Function	GO:0005515	protein binding	IPI	J:153063
Molecular Function	GO:0005515	protein binding	IPI	J:153063
Molecular Function	GO:0003713	transcription coactivator activity	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0045171	intercellular bridge	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:164563
Cellular Component	GO:0032993	protein-DNA complex	ISO	J:164563
Biological Process	GO:0002526	acute inflammatory response	IMP	J:88958
Biological Process	GO:0044346	fibroblast apoptotic process	IMP	J:133728
Biological Process	GO:0048144	fibroblast proliferation	IMP	J:133728
Biological Process	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	IMP	J:133728
Biological Process	GO:0008584	male gonad development	IMP	J:140899
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:164563
Biological Process	GO:1902902	negative regulation of autophagosome assembly	ISO	J:164563
Biological Process	GO:0010507	negative regulation of autophagy	IMP	J:271800
Biological Process	GO:0010507	negative regulation of autophagy	ISO	J:155856
Biological Process	GO:0010507	negative regulation of autophagy	ISO	J:164563
Biological Process	GO:0010667	negative regulation of cardiac muscle cell apoptotic process	ISO	J:155856
Biological Process	GO:0010667	negative regulation of cardiac muscle cell apoptotic process	ISO	J:164563
Biological Process	GO:0045786	negative regulation of cell cycle	ISO	J:164563
Biological Process	GO:0045786	negative regulation of cell cycle	IBA	J:265628
Biological Process	GO:0045786	negative regulation of cell cycle	IMP	J:153063
Biological Process	GO:0008285	negative regulation of cell population proliferation	IBA	J:265628
Biological Process	GO:0043433	negative regulation of DNA-binding transcription factor activity	ISO	J:164563
Biological Process	GO:0043433	negative regulation of DNA-binding transcription factor activity	ISO	J:155856
Biological Process	GO:1904036	negative regulation of epithelial cell apoptotic process	IMP	J:271708
Biological Process	GO:0050680	negative regulation of epithelial cell proliferation	IMP	J:271708
Biological Process	GO:0048147	negative regulation of fibroblast proliferation	IMP	J:133728
Biological Process	GO:0045820	negative regulation of glycolytic process	ISO	J:164563
Biological Process	GO:0062099	negative regulation of programmed necrotic cell death	ISO	J:164563
Biological Process	GO:1904691	negative regulation of type B pancreatic cell proliferation	IMP	J:203693
Biological Process	GO:0045787	positive regulation of cell cycle	ISO	J:164563
Biological Process	GO:2000271	positive regulation of fibroblast apoptotic process	IMP	J:133728
Biological Process	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway	ISO	J:155856
Biological Process	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway	ISO	J:164563
Biological Process	GO:0150078	positive regulation of neuroinflammatory response	IMP	J:156137
Biological Process	GO:0043525	positive regulation of neuron apoptotic process	ISO	J:155856
Biological Process	GO:1903862	positive regulation of oxidative phosphorylation	ISO	J:164563
Biological Process	GO:1901800	positive regulation of proteasomal protein catabolic process	ISO	J:164563
Biological Process	GO:0031401	positive regulation of protein modification process	IMP	J:153063
Biological Process	GO:0006473	protein acetylation	IMP	J:153063
Biological Process	GO:0065003	protein-containing complex assembly	IMP	J:153063
Biological Process	GO:0010506	regulation of autophagy	ISO	J:155856
Biological Process	GO:2000194	regulation of female gonad development	IMP	J:140899
Biological Process	GO:1905897	regulation of response to endoplasmic reticulum stress	ISO	J:164563
Biological Process	GO:1905897	regulation of response to endoplasmic reticulum stress	ISO	J:155856
Biological Process	GO:0009636	response to toxic substance	IMP	J:88958
Biological Process	GO:0035914	skeletal muscle cell differentiation	IMP	J:153063