GO Annotations Graph

• Symbol: Hdac7
• Name: histone deacetylase 7
• ID: MGI:1891835

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0071889	14-3-3 protein binding	ISO	J:164563
Molecular Function	GO:0003682	chromatin binding	IDA	J:104056
Molecular Function	GO:0140297	DNA-binding transcription factor binding	ISO	J:164563
Molecular Function	GO:0140297	DNA-binding transcription factor binding	TAS	J:113927
Molecular Function	GO:0004407	histone deacetylase activity	TAS	J:113927
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:200333
Molecular Function	GO:0005515	protein binding	IPI	J:201261
Molecular Function	GO:0005515	protein binding	IPI	J:248240
Molecular Function	GO:0005515	protein binding	IPI	J:200315
Molecular Function	GO:0005515	protein binding	IPI	J:64684
Molecular Function	GO:0005515	protein binding	IPI	J:64684
Molecular Function	GO:0005515	protein binding	IPI	J:102395
Molecular Function	GO:0019901	protein kinase binding	ISO	J:164563
Molecular Function	GO:0005080	protein kinase C binding	ISO	J:164563
Molecular Function	GO:0033558	protein lysine deacetylase activity	ISO	J:164563
Molecular Function	GO:0003714	transcription corepressor activity	IDA	J:64684
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	TAS	J:113927
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0000118	histone deacetylase complex	TAS	J:113927
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	TAS	J:113927
Biological Process	GO:0042113	B cell activation	TAS	J:113927
Biological Process	GO:0030183	B cell differentiation	TAS	J:113927
Biological Process	GO:0007043	cell-cell junction assembly	IMP	J:116008
Biological Process	GO:0006325	chromatin organization	TAS	J:113927
Biological Process	GO:0016575	histone deacetylation	IEA	J:72247
Biological Process	GO:0006954	inflammatory response	TAS	J:113927
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	TAS	J:113927
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:102395
Biological Process	GO:0032703	negative regulation of interleukin-2 production	ISO	J:164563
Biological Process	GO:1901215	negative regulation of neuron death	ISO	J:155856
Biological Process	GO:1901223	negative regulation of NIK/NF-kappaB signaling	ISO	J:164563
Biological Process	GO:0045668	negative regulation of osteoblast differentiation	ISO	J:164563
Biological Process	GO:0045843	negative regulation of striated muscle tissue development	TAS	J:113927
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:64684
Biological Process	GO:0007399	nervous system development	TAS	J:113927
Biological Process	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis	ISO	J:164563
Biological Process	GO:0006476	protein deacetylation	ISO	J:164563
Biological Process	GO:0001570	vasculogenesis	IMP	J:116008