GO Annotations Graph

• Symbol: Pias1
• Name: protein inhibitor of activated STAT 1
• ID: MGI:1913125

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0140297	DNA-binding transcription factor binding	IPI	J:219047
Molecular Function	GO:0019899	enzyme binding	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:196239
Molecular Function	GO:0005515	protein binding	IPI	J:245382
Molecular Function	GO:0005515	protein binding	IPI	J:101497
Molecular Function	GO:0005515	protein binding	IPI	J:172885
Molecular Function	GO:0005515	protein binding	IPI	J:112691
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:155856
Molecular Function	GO:0061665	SUMO ligase activity	ISO	J:164563
Molecular Function	GO:0061665	SUMO ligase activity	IBA	J:265628
Molecular Function	GO:0019789	SUMO transferase activity	ISO	J:164563
Molecular Function	GO:0019789	SUMO transferase activity	EXP	J:262338
Molecular Function	GO:0019789	SUMO transferase activity	EXP	J:140756
Molecular Function	GO:0019789	SUMO transferase activity	EXP	J:262418
Molecular Function	GO:0019789	SUMO transferase activity	EXP	J:262359
Molecular Function	GO:0019789	SUMO transferase activity	ISO	J:155856
Molecular Function	GO:0003712	transcription coregulator activity	IBA	J:265628
Molecular Function	GO:0003714	transcription corepressor activity	ISO	J:55317
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0031625	ubiquitin protein ligase binding	IPI	J:172990
Molecular Function	GO:0008270	zinc ion binding	IEA	J:72247
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-4717507
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IDA	J:112691
Cellular Component	GO:0016605	PML body	IDA	J:196239
Biological Process	GO:0045444	fat cell differentiation	IDA	J:219047
Biological Process	GO:0000082	G1/S transition of mitotic cell cycle	ISO	J:155856
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:155856
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:101497
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:155856
Biological Process	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	IMP	J:196239
Biological Process	GO:0033235	positive regulation of protein sumoylation	ISO	J:164563
Biological Process	GO:0033235	positive regulation of protein sumoylation	ISO	J:155856
Biological Process	GO:0051152	positive regulation of smooth muscle cell differentiation	ISO	J:155856
Biological Process	GO:0016925	protein sumoylation	ISO	J:164563
Biological Process	GO:0016925	protein sumoylation	IDA	J:196239
Biological Process	GO:0016925	protein sumoylation	IDA	J:219047
Biological Process	GO:0016925	protein sumoylation	IBA	J:265628
Biological Process	GO:0065004	protein-DNA complex assembly	ISO	J:155856
Biological Process	GO:0007259	receptor signaling pathway via JAK-STAT	ISO	J:55317
Biological Process	GO:0042127	regulation of cell population proliferation	IMP	J:196239
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0008542	visual learning	ISO	J:155856