GO Annotations Graph

• Symbol: Pias3
• Name: protein inhibitor of activated STAT 3
• ID: MGI:1913126

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0035255	ionotropic glutamate receptor binding	ISO	J:155856
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0015459	potassium channel regulator activity	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:177205
Molecular Function	GO:0005515	protein binding	IPI	J:213908
Molecular Function	GO:0005515	protein binding	IPI	J:142156
Molecular Function	GO:0005515	protein binding	IPI	J:175118
Molecular Function	GO:0005515	protein binding	IPI	J:175118
Molecular Function	GO:0005515	protein binding	IPI	J:145836
Molecular Function	GO:0005515	protein binding	IPI	J:145836
Molecular Function	GO:0005515	protein binding	IPI	J:145836
Molecular Function	GO:0005515	protein binding	IPI	J:145836
Molecular Function	GO:0005515	protein binding	IPI	J:112468
Molecular Function	GO:0061665	SUMO ligase activity	IBA	J:265628
Molecular Function	GO:0019789	SUMO transferase activity	ISO	J:164563
Molecular Function	GO:0019789	SUMO transferase activity	IDA	J:97581
Molecular Function	GO:0003712	transcription coregulator activity	IBA	J:265628
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0044325	transmembrane transporter binding	ISO	J:155856
Molecular Function	GO:0008270	zinc ion binding	IEA	J:72247
Cellular Component	GO:0005737	cytoplasm	IDA	J:177205
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IDA	J:177205
Cellular Component	GO:0005634	nucleus	IDA	J:86405
Cellular Component	GO:0045202	synapse	ISO	J:155856
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:145836
Biological Process	GO:0010629	negative regulation of gene expression	IDA	J:145836
Biological Process	GO:0010629	negative regulation of gene expression	IDA	J:145836
Biological Process	GO:0045671	negative regulation of osteoclast differentiation	IMP	J:145836
Biological Process	GO:0045671	negative regulation of osteoclast differentiation	IDA	J:145836
Biological Process	GO:0033234	negative regulation of protein sumoylation	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:145836
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:145836
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:145836
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:155856
Biological Process	GO:0045838	positive regulation of membrane potential	ISO	J:155856
Biological Process	GO:0033235	positive regulation of protein sumoylation	ISO	J:164563
Biological Process	GO:0016925	protein sumoylation	IBA	J:265628
Biological Process	GO:0016925	protein sumoylation	IDA	J:97581
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0071847	TNFSF11-mediated signaling pathway	IDA	J:145836