GO Annotations Graph

• Symbol: Psmd14
• Name: proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
• ID: MGI:1913284

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0061133	endopeptidase activator activity	ISO	J:164563
Molecular Function	GO:0004175	endopeptidase activity	ISS	J:64935
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0061578	K63-linked deubiquitinase activity	IEA	J:72247
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0140492	metal-dependent deubiquitinase activity	ISO	J:164563
Molecular Function	GO:0008237	metallopeptidase activity	IBA	J:265628
Molecular Function	GO:0008233	peptidase activity	IEA	J:60000
Molecular Function	GO:0070628	proteasome binding	ISO	J:164563
Molecular Function	GO:0070628	proteasome binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:200421
Molecular Function	GO:0005515	protein binding	IPI	J:112707
Cellular Component	GO:0031597	cytosolic proteasome complex	ISO	J:155856
Cellular Component	GO:0022624	proteasome accessory complex	IDA	J:188902
Cellular Component	GO:0000502	proteasome complex	ISO	J:164563
Cellular Component	GO:0000502	proteasome complex	ISS	J:64935
Cellular Component	GO:0000502	proteasome complex	IDA	J:112707
Cellular Component	GO:0008541	proteasome regulatory particle, lid subcomplex	ISO	J:164563
Cellular Component	GO:0008541	proteasome regulatory particle, lid subcomplex	IBA	J:265628
Biological Process	GO:0006974	DNA damage response	IEA	J:60000
Biological Process	GO:0006281	DNA repair	IEA	J:60000
Biological Process	GO:0000724	double-strand break repair via homologous recombination	ISO	J:164563
Biological Process	GO:0006303	double-strand break repair via nonhomologous end joining	ISO	J:164563
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	IBA	J:265628
Biological Process	GO:0016579	protein deubiquitination	IBA	J:265628
Biological Process	GO:0070536	protein K63-linked deubiquitination	ISO	J:164563
Biological Process	GO:0006508	proteolysis	IEA	J:60000
Biological Process	GO:0061136	regulation of proteasomal protein catabolic process	ISO	J:164563