GO Annotations Graph

• Symbol: Sostdc1
• Name: sclerostin domain containing 1
• ID: MGI:1913292

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0036122	BMP binding	ISO	J:164563
Molecular Function	GO:0036122	BMP binding	IBA	J:265628
Molecular Function	GO:0098821	BMP receptor activity	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:86665
Molecular Function	GO:0005515	protein binding	IPI	J:86665
Molecular Function	GO:0005515	protein binding	IPI	J:86665
Molecular Function	GO:0005515	protein binding	IPI	J:86665
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Cellular Component	GO:0005615	extracellular space	IDA	J:86665
Biological Process	GO:0030509	BMP signaling pathway	IDA	J:101382
Biological Process	GO:0030509	BMP signaling pathway	IGI	J:101382
Biological Process	GO:0030509	BMP signaling pathway	IGI	J:101382
Biological Process	GO:0030509	BMP signaling pathway	IDA	J:101382
Biological Process	GO:0060070	canonical Wnt signaling pathway	IMP	J:183911
Biological Process	GO:0045165	cell fate commitment	IMP	J:183911
Biological Process	GO:0072148	epithelial cell fate commitment	IMP	J:183911
Biological Process	GO:0031069	hair follicle morphogenesis	IMP	J:183911
Biological Process	GO:0060648	mammary gland bud morphogenesis	IMP	J:183911
Biological Process	GO:0030514	negative regulation of BMP signaling pathway	ISO	J:164563
Biological Process	GO:0030514	negative regulation of BMP signaling pathway	IBA	J:265628
Biological Process	GO:0030514	negative regulation of BMP signaling pathway	IDA	J:101382
Biological Process	GO:0030514	negative regulation of BMP signaling pathway	IDA	J:86665
Biological Process	GO:0030514	negative regulation of BMP signaling pathway	IGI	J:101382
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	IMP	J:183911
Biological Process	GO:0010454	negative regulation of cell fate commitment	IMP	J:183911
Biological Process	GO:2000016	negative regulation of determination of dorsal identity	ISO	J:164563
Biological Process	GO:0045662	negative regulation of myoblast differentiation	ISO	J:164563
Biological Process	GO:0030178	negative regulation of Wnt signaling pathway	ISO	J:164563
Biological Process	GO:0030178	negative regulation of Wnt signaling pathway	IBA	J:265628
Biological Process	GO:0042475	odontogenesis of dentin-containing tooth	IGI	J:101382
Biological Process	GO:0042475	odontogenesis of dentin-containing tooth	IMP	J:101382
Biological Process	GO:0007389	pattern specification process	IMP	J:101382
Biological Process	GO:0016055	Wnt signaling pathway	IEA	J:60000