GO Annotations Graph

• Symbol: Apoa5
• Name: apolipoprotein A-V
• ID: MGI:1913363

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008047	enzyme activator activity	ISO	J:164563
Molecular Function	GO:0019899	enzyme binding	ISO	J:164563
Molecular Function	GO:0008201	heparin binding	ISO	J:164563
Molecular Function	GO:0060229	lipase activator activity	ISO	J:164563
Molecular Function	GO:0035473	lipase binding	ISO	J:164563
Molecular Function	GO:0008289	lipid binding	ISO	J:164563
Molecular Function	GO:0060230	lipoprotein lipase activator activity	ISO	J:164563
Molecular Function	GO:0070325	lipoprotein particle receptor binding	ISO	J:164563
Molecular Function	GO:0050750	low-density lipoprotein particle receptor binding	ISO	J:164563
Molecular Function	GO:0031210	phosphatidylcholine binding	ISO	J:164563
Molecular Function	GO:0031210	phosphatidylcholine binding	IBA	J:265628
Molecular Function	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity	IBA	J:265628
Molecular Function	GO:0005543	phospholipid binding	ISO	J:164563
Cellular Component	GO:0042627	chylomicron	ISO	J:164563
Cellular Component	GO:0042627	chylomicron	IBA	J:265628
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-6784616
Cellular Component	GO:0005768	endosome	IEA	J:60000
Cellular Component	GO:0005576	extracellular region	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0005794	Golgi apparatus	IEA	J:60000
Cellular Component	GO:0034364	high-density lipoprotein particle	ISO	J:164563
Cellular Component	GO:0034364	high-density lipoprotein particle	IBA	J:265628
Cellular Component	GO:0034361	very-low-density lipoprotein particle	ISO	J:164563
Biological Process	GO:0055090	acylglycerol homeostasis	ISO	J:164563
Biological Process	GO:0055090	acylglycerol homeostasis	IMP	J:72092
Biological Process	GO:0033344	cholesterol efflux	IBA	J:265628
Biological Process	GO:0042632	cholesterol homeostasis	ISO	J:164563
Biological Process	GO:0042632	cholesterol homeostasis	IBA	J:265628
Biological Process	GO:0006869	lipid transport	ISO	J:164563
Biological Process	GO:0006869	lipid transport	ISO	J:155856
Biological Process	GO:0042157	lipoprotein metabolic process	IEA	J:72247
Biological Process	GO:0033700	phospholipid efflux	IBA	J:265628
Biological Process	GO:0045723	positive regulation of fatty acid biosynthetic process	ISO	J:164563
Biological Process	GO:0045723	positive regulation of fatty acid biosynthetic process	IBA	J:265628
Biological Process	GO:0050996	positive regulation of lipid catabolic process	ISO	J:164563
Biological Process	GO:0051006	positive regulation of lipoprotein lipase activity	ISO	J:164563
Biological Process	GO:0051006	positive regulation of lipoprotein lipase activity	IBA	J:265628
Biological Process	GO:0010898	positive regulation of triglyceride catabolic process	ISO	J:164563
Biological Process	GO:0010898	positive regulation of triglyceride catabolic process	IBA	J:265628
Biological Process	GO:0010902	positive regulation of very-low-density lipoprotein particle remodeling	ISO	J:164563
Biological Process	GO:0019433	triglyceride catabolic process	ISO	J:164563
Biological Process	GO:0070328	triglyceride homeostasis	ISO	J:164563
Biological Process	GO:0070328	triglyceride homeostasis	IBA	J:265628
Biological Process	GO:0006641	triglyceride metabolic process	ISO	J:164563
Biological Process	GO:0006641	triglyceride metabolic process	IMP	J:116807
Biological Process	GO:0034370	triglyceride-rich lipoprotein particle remodeling	IMP	J:116807
Biological Process	GO:0034372	very-low-density lipoprotein particle remodeling	IBA	J:265628