GO Annotations Graph

• Symbol: Aqp11
• Name: aquaporin 11
• ID: MGI:1913583

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0015267	channel activity	IBA	J:265628
Molecular Function	GO:0015254	glycerol channel activity	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0015250	water channel activity	IDA	J:279944
Molecular Function	GO:0015250	water channel activity	ISO	J:164563
Molecular Function	GO:0015250	water channel activity	IDA	J:188552
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IDA	J:100522
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:279938
Cellular Component	GO:0005783	endoplasmic reticulum	IMP	J:226888
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:100522
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0048471	perinuclear region of cytoplasm	IDA	J:100522
Cellular Component	GO:0005886	plasma membrane	IDA	J:279938
Biological Process	GO:0048388	endosomal lumen acidification	IMP	J:100522
Biological Process	GO:0080170	hydrogen peroxide transmembrane transport	ISO	J:164563
Biological Process	GO:0032364	intracellular oxygen homeostasis	IMP	J:281183
Biological Process	GO:0009992	intracellular water homeostasis	ISO	J:164563
Biological Process	GO:0009992	intracellular water homeostasis	IDA	J:279938
Biological Process	GO:0009992	intracellular water homeostasis	IDA	J:279944
Biological Process	GO:0001822	kidney development	IMP	J:100522
Biological Process	GO:0050680	negative regulation of epithelial cell proliferation	IMP	J:280414
Biological Process	GO:1904293	negative regulation of ERAD pathway	IMP	J:140244
Biological Process	GO:1903573	negative regulation of response to endoplasmic reticulum stress	IMP	J:140244
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0006486	protein glycosylation	IMP	J:226888
Biological Process	GO:0051260	protein homooligomerization	IDA	J:279938
Biological Process	GO:0051260	protein homooligomerization	ISO	J:164563
Biological Process	GO:0006612	protein targeting to membrane	IMP	J:226888
Biological Process	GO:0072014	proximal tubule development	IMP	J:280414
Biological Process	GO:0072014	proximal tubule development	IMP	J:169660
Biological Process	GO:0055085	transmembrane transport	IEA	J:72247
Biological Process	GO:0006833	water transport	IDA	J:188552