GO Annotations Graph

• Symbol: Fis1
• Name: fission, mitochondrial 1
• ID: MGI:1913687

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0008289	lipid binding	ISO	J:164563
Molecular Function	GO:0060090	molecular adaptor activity	ISO	J:164563
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005741	mitochondrial outer membrane	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	ISO	J:155856
Cellular Component	GO:0005739	mitochondrion	HDA	J:151002
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	IDA	J:113296
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005778	peroxisomal membrane	ISO	J:164563
Cellular Component	GO:0005778	peroxisomal membrane	ISO	J:155856
Cellular Component	GO:0005777	peroxisome	ISO	J:155856
Cellular Component	GO:0005777	peroxisome	ISS	J:116241
Cellular Component	GO:0005777	peroxisome	ISO	J:164563
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Biological Process	GO:0006915	apoptotic process	IEA	J:60000
Biological Process	GO:0000422	autophagy of mitochondrion	ISO	J:164563
Biological Process	GO:0000422	autophagy of mitochondrion	IBA	J:265628
Biological Process	GO:0035584	calcium-mediated signaling using intracellular calcium source	ISO	J:164563
Biological Process	GO:1901653	cellular response to peptide	ISO	J:155856
Biological Process	GO:0000266	mitochondrial fission	IMP	J:200469
Biological Process	GO:0000266	mitochondrial fission	ISO	J:164563
Biological Process	GO:0000266	mitochondrial fission	IBA	J:265628
Biological Process	GO:0043653	mitochondrial fragmentation involved in apoptotic process	ISO	J:164563
Biological Process	GO:0043653	mitochondrial fragmentation involved in apoptotic process	ISO	J:155856
Biological Process	GO:0043653	mitochondrial fragmentation involved in apoptotic process	IBA	J:265628
Biological Process	GO:0008053	mitochondrial fusion	ISO	J:164563
Biological Process	GO:0070584	mitochondrion morphogenesis	ISO	J:164563
Biological Process	GO:0070584	mitochondrion morphogenesis	ISO	J:167998
Biological Process	GO:1903579	negative regulation of ATP metabolic process	ISO	J:164563
Biological Process	GO:0032471	negative regulation of endoplasmic reticulum calcium ion concentration	ISO	J:164563
Biological Process	GO:2000192	negative regulation of fatty acid transport	ISO	J:164563
Biological Process	GO:0016559	peroxisome fission	ISO	J:164563
Biological Process	GO:0016559	peroxisome fission	ISS	J:188899
Biological Process	GO:0016559	peroxisome fission	IBA	J:265628
Biological Process	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	ISO	J:164563
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	ISO	J:164563
Biological Process	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway	ISO	J:164563
Biological Process	GO:0051561	positive regulation of mitochondrial calcium ion concentration	ISO	J:164563
Biological Process	GO:0090141	positive regulation of mitochondrial fission	ISO	J:164563
Biological Process	GO:0090141	positive regulation of mitochondrial fission	ISO	J:155856
Biological Process	GO:0043525	positive regulation of neuron apoptotic process	ISO	J:155856
Biological Process	GO:0090314	positive regulation of protein targeting to membrane	ISO	J:164563
Biological Process	GO:0006626	protein targeting to mitochondrion	ISO	J:164563
Biological Process	GO:0010821	regulation of mitochondrion organization	ISO	J:164563
Biological Process	GO:0001836	release of cytochrome c from mitochondria	ISO	J:164563
Biological Process	GO:0034976	response to endoplasmic reticulum stress	ISO	J:155856