GO Annotations Graph

• Symbol: Lamtor1
• Name: late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
• ID: MGI:1913758

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0051020	GTPase binding	ISO	J:164563
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	ISO	J:164563
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	IBA	J:265628
Molecular Function	GO:0060090	molecular adaptor activity	ISO	J:164563
Molecular Function	GO:0060090	molecular adaptor activity	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:274778
Molecular Function	GO:0005515	protein binding	IPI	J:168293
Molecular Function	GO:0005515	protein binding	IPI	J:216883
Cellular Component	GO:0005768	endosome	IEA	J:60000
Cellular Component	GO:0031902	late endosome membrane	ISO	J:155856
Cellular Component	GO:0031902	late endosome membrane	NAS	J:320089
Cellular Component	GO:0031902	late endosome membrane	ISO	J:155856
Cellular Component	GO:0005765	lysosomal membrane	NAS	J:320116
Cellular Component	GO:0005764	lysosome	ISO	J:164563
Cellular Component	GO:0005764	lysosome	IBA	J:265628
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0045121	membrane raft	ISO	J:155856
Cellular Component	GO:0045121	membrane raft	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Cellular Component	GO:0071986	Ragulator complex	ISO	J:164563
Cellular Component	GO:0071986	Ragulator complex	IBA	J:265628
Biological Process	GO:0071230	cellular response to amino acid stimulus	ISO	J:164563
Biological Process	GO:0071230	cellular response to amino acid stimulus	IBA	J:265628
Biological Process	GO:0042632	cholesterol homeostasis	ISO	J:164563
Biological Process	GO:0016197	endosomal transport	IMP	J:168293
Biological Process	GO:0007032	endosome organization	IMP	J:168293
Biological Process	GO:0032418	lysosome localization	IMP	J:168293
Biological Process	GO:0007040	lysosome organization	IMP	J:168293
Biological Process	GO:0043410	positive regulation of MAPK cascade	IMP	J:168293
Biological Process	GO:0043410	positive regulation of MAPK cascade	IBA	J:265628
Biological Process	GO:0032008	positive regulation of TOR signaling	ISO	J:164563
Biological Process	GO:0008104	protein localization	IMP	J:168293
Biological Process	GO:0008104	protein localization	ISO	J:164563
Biological Process	GO:0001558	regulation of cell growth	ISO	J:164563
Biological Process	GO:0010874	regulation of cholesterol efflux	ISO	J:164563
Biological Process	GO:0060620	regulation of cholesterol import	ISO	J:164563
Biological Process	GO:0001919	regulation of receptor recycling	IMP	J:168293
Biological Process	GO:0001919	regulation of receptor recycling	IBA	J:265628
Biological Process	GO:0038202	TORC1 signaling	NAS	J:320116