GO Annotations Graph

• Symbol: Tab1
• Name: TGF-beta activated kinase 1/MAP3K7 binding protein 1
• ID: MGI:1913763

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0019209	kinase activator activity	IMP	J:80766
Molecular Function	GO:0048273	mitogen-activated protein kinase p38 binding	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:201312
Molecular Function	GO:0005515	protein binding	IPI	J:166091
Molecular Function	GO:0005515	protein binding	IPI	J:149244
Molecular Function	GO:0005515	protein binding	IPI	J:148055
Molecular Function	GO:0005515	protein binding	IPI	J:215973
Molecular Function	GO:0004722	protein serine/threonine phosphatase activity	IEA	J:72247
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-209329
Cellular Component	GO:0005829	cytosol	IBA	J:265628
Cellular Component	GO:0016607	nuclear speck	ISO	J:164563
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Biological Process	GO:0035904	aorta development	IMP	J:222159
Biological Process	GO:0003279	cardiac septum development	IMP	J:222159
Biological Process	GO:0060976	coronary vasculature development	IMP	J:222159
Biological Process	GO:0003007	heart morphogenesis	IMP	J:80766
Biological Process	GO:0001701	in utero embryonic development	IMP	J:80766
Biological Process	GO:0030324	lung development	IMP	J:80766
Biological Process	GO:0043406	positive regulation of MAP kinase activity	ISO	J:155856
Biological Process	GO:0043410	positive regulation of MAPK cascade	IMP	J:80766
Biological Process	GO:0071902	positive regulation of protein serine/threonine kinase activity	ISO	J:164563
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	IMP	J:80766