Nipbl GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Nipbl
NIPBL cohesin loading factor
MGI:1913976

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IBA	J:265628
Molecular Function	GO:0003682	chromatin binding	IDA	J:164442
Molecular Function	GO:0003682	chromatin binding	IDA	J:164442
Molecular Function	GO:0070087	chromo shadow domain binding	ISO	J:164563
Molecular Function	GO:0061775	cohesin loader activity	ISO	J:164563
Molecular Function	GO:0061775	cohesin loader activity	IMP	J:250426
Molecular Function	GO:0042826	histone deacetylase binding	ISO	J:164563
Molecular Function	GO:0036033	mediator complex binding	IDA	J:164442
Molecular Function	GO:1990841	promoter-specific chromatin binding	IDA	J:243510
Molecular Function	GO:0005515	protein binding	IPI	J:243510
Cellular Component	GO:0000785	chromatin	IDA	J:204095
Cellular Component	GO:0005694	chromosome	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0032039	integrator complex	IDA	J:243510
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:250426
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0090694	Scc2-Scc4 cohesin loading complex	ISO	J:164563
Cellular Component	GO:0090694	Scc2-Scc4 cohesin loading complex	IBA	J:265628
Cellular Component	GO:0032116	SMC loading complex	ISO	J:164563
Biological Process	GO:0007420	brain development	ISO	J:164563
Biological Process	GO:0007420	brain development	IBA	J:265628
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0071481	cellular response to X-ray	ISO	J:164563
Biological Process	GO:0050890	cognition	ISO	J:164563
Biological Process	GO:0048589	developmental growth	ISO	J:164563
Biological Process	GO:0048565	digestive tract development	IBA	J:265628
Biological Process	GO:0006974	DNA damage response	ISO	J:164563
Biological Process	GO:0042471	ear morphogenesis	ISO	J:164563
Biological Process	GO:0048701	embryonic cranial skeleton morphogenesis	IMP	J:154117
Biological Process	GO:0048557	embryonic digestive tract morphogenesis	ISO	J:164563
Biological Process	GO:0035115	embryonic forelimb morphogenesis	ISO	J:164563
Biological Process	GO:0048703	embryonic viscerocranium morphogenesis	IBA	J:265628
Biological Process	GO:0048703	embryonic viscerocranium morphogenesis	IMP	J:154117
Biological Process	GO:0034087	establishment of mitotic sister chromatid cohesion	IBA	J:265628
Biological Process	GO:0071169	establishment of protein localization to chromatin	IBA	J:265628
Biological Process	GO:0035261	external genitalia morphogenesis	ISO	J:164563
Biological Process	GO:0048592	eye morphogenesis	ISO	J:164563
Biological Process	GO:0060325	face morphogenesis	ISO	J:164563
Biological Process	GO:0045444	fat cell differentiation	IMP	J:154117
Biological Process	GO:0035136	forelimb morphogenesis	ISO	J:164563
Biological Process	GO:0061010	gallbladder development	ISO	J:164563
Biological Process	GO:0007507	heart development	IMP	J:154117
Biological Process	GO:0003007	heart morphogenesis	ISO	J:164563
Biological Process	GO:0003007	heart morphogenesis	IBA	J:265628
Biological Process	GO:0034088	maintenance of mitotic sister chromatid cohesion	ISO	J:164563
Biological Process	GO:0061780	mitotic cohesin loading	IEA	J:72247
Biological Process	GO:0007064	mitotic sister chromatid cohesion	ISO	J:164563
Biological Process	GO:0000070	mitotic sister chromatid segregation	IMP	J:250426
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0003151	outflow tract morphogenesis	ISO	J:164563
Biological Process	GO:0031065	positive regulation of histone deacetylation	ISO	J:164563
Biological Process	GO:0040018	positive regulation of multicellular organism growth	IMP	J:154117
Biological Process	GO:2001224	positive regulation of neuron migration	IMP	J:243510
Biological Process	GO:0045778	positive regulation of ossification	IMP	J:154117
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:204095
Biological Process	GO:0008104	protein localization	ISO	J:164563
Biological Process	GO:0048638	regulation of developmental growth	ISO	J:164563
Biological Process	GO:0045995	regulation of embryonic development	ISO	J:164563
Biological Process	GO:0010468	regulation of gene expression	IEA	J:72247
Biological Process	GO:0042634	regulation of hair cycle	ISO	J:164563
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IMP	J:243510
Biological Process	GO:1990414	replication-born double-strand break repair via sister chromatid exchange	IBA	J:265628
Biological Process	GO:0007605	sensory perception of sound	ISO	J:164563
Biological Process	GO:0035019	somatic stem cell population maintenance	IMP	J:164442
Biological Process	GO:0061038	uterus morphogenesis	ISO	J:164563

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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