GO Annotations Graph

• Symbol: Oma1
• Name: OMA1 zinc metallopeptidase
• ID: MGI:1914263

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0008289	lipid binding	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0004222	metalloendopeptidase activity	IDA	J:208034
Molecular Function	GO:0004222	metalloendopeptidase activity	ISO	J:164563
Molecular Function	GO:0004222	metalloendopeptidase activity	IDA	J:289068
Molecular Function	GO:0004222	metalloendopeptidase activity	IMP	J:184716
Molecular Function	GO:0004222	metalloendopeptidase activity	IBA	J:265628
Molecular Function	GO:0008237	metallopeptidase activity	IEA	J:60000
Molecular Function	GO:0008233	peptidase activity	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005743	mitochondrial inner membrane	ISO	J:164563
Cellular Component	GO:0005743	mitochondrial inner membrane	IDA	J:208034
Cellular Component	GO:0005743	mitochondrial inner membrane	IBA	J:265628
Cellular Component	GO:0031966	mitochondrial membrane	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	HDA	J:151002
Cellular Component	GO:0005739	mitochondrion	IDA	J:156874
Biological Process	GO:0042407	cristae formation	IGI	J:156874
Biological Process	GO:0042407	cristae formation	IGI	J:156874
Biological Process	GO:0002024	diet induced thermogenesis	IMP	J:184716
Biological Process	GO:0097009	energy homeostasis	IMP	J:184716
Biological Process	GO:0006006	glucose metabolic process	IMP	J:184716
Biological Process	GO:0140468	HRI-mediated signaling	ISO	J:164563
Biological Process	GO:0140467	integrated stress response signaling	ISO	J:164563
Biological Process	GO:0006629	lipid metabolic process	IMP	J:184716
Biological Process	GO:0034982	mitochondrial protein processing	ISO	J:164563
Biological Process	GO:0034982	mitochondrial protein processing	IDA	J:208034
Biological Process	GO:0034982	mitochondrial protein processing	IDA	J:289068
Biological Process	GO:0034982	mitochondrial protein processing	IBA	J:265628
Biological Process	GO:0034982	mitochondrial protein processing	IMP	J:156874
Biological Process	GO:0033108	mitochondrial respiratory chain complex assembly	IMP	J:289449
Biological Process	GO:0007005	mitochondrion organization	IGI	J:156874
Biological Process	GO:0007005	mitochondrion organization	IGI	J:156874
Biological Process	GO:0010637	negative regulation of mitochondrial fusion	ISO	J:164563
Biological Process	GO:0010637	negative regulation of mitochondrial fusion	IMP	J:184716
Biological Process	GO:0043065	positive regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0120162	positive regulation of cold-induced thermogenesis	IMP	J:184716
Biological Process	GO:0016540	protein autoprocessing	IDA	J:289068
Biological Process	GO:0016540	protein autoprocessing	IDA	J:208034
Biological Process	GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	ISO	J:164563
Biological Process	GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	IBA	J:265628
Biological Process	GO:0006508	proteolysis	IEA	J:72247
Biological Process	GO:0006508	proteolysis	IEA	J:60000
Biological Process	GO:1903850	regulation of cristae formation	ISO	J:164563
Biological Process	GO:0031638	zymogen activation	IDA	J:208034
Biological Process	GO:0031638	zymogen activation	IDA	J:289068