GO Annotations Graph

• Symbol: Cdt1
• Name: chromatin licensing and DNA replication factor 1
• ID: MGI:1914427

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	ISO	J:164563
Molecular Function	GO:0003677	DNA binding	IDA	J:79742
Molecular Function	GO:0003677	DNA binding	IBA	J:265628
Molecular Function	GO:0070182	DNA polymerase binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:116246
Molecular Function	GO:0005515	protein binding	IPI	J:79742
Molecular Function	GO:0005515	protein binding	IPI	J:314075
Cellular Component	GO:0005694	chromosome	IEA	J:60000
Cellular Component	GO:0000775	chromosome, centromeric region	IEA	J:60000
Cellular Component	GO:0000776	kinetochore	ISO	J:164563
Cellular Component	GO:0016604	nuclear body	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:114148
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	ISO	J:208295
Biological Process	GO:0051315	attachment of mitotic spindle microtubules to kinetochore	ISO	J:164563
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0051301	cell division	ISO	J:164563
Biological Process	GO:0007059	chromosome segregation	ISO	J:164563
Biological Process	GO:1902426	deactivation of mitotic spindle assembly checkpoint	ISO	J:164563
Biological Process	GO:0006260	DNA replication	IEA	J:60000
Biological Process	GO:0000076	DNA replication checkpoint signaling	ISO	J:164563
Biological Process	GO:0000076	DNA replication checkpoint signaling	IDA	J:79742
Biological Process	GO:0000076	DNA replication checkpoint signaling	IBA	J:265628
Biological Process	GO:0071163	DNA replication preinitiation complex assembly	ISO	J:164563
Biological Process	GO:0071163	DNA replication preinitiation complex assembly	IBA	J:265628
Biological Process	GO:0051383	kinetochore organization	ISO	J:164563
Biological Process	GO:0000278	mitotic cell cycle	ISO	J:164563
Biological Process	GO:0000278	mitotic cell cycle	IBA	J:265628
Biological Process	GO:0045786	negative regulation of cell cycle	ISO	J:164563
Biological Process	GO:2000104	negative regulation of DNA-templated DNA replication	ISO	J:164563
Biological Process	GO:1905341	negative regulation of protein localization to kinetochore	ISO	J:164563
Biological Process	GO:0035563	positive regulation of chromatin binding	ISO	J:164563
Biological Process	GO:0045740	positive regulation of DNA replication	ISO	J:164563
Biological Process	GO:2000105	positive regulation of DNA-templated DNA replication	ISO	J:164563
Biological Process	GO:1905342	positive regulation of protein localization to kinetochore	ISO	J:164563
Biological Process	GO:0031334	positive regulation of protein-containing complex assembly	ISO	J:164563
Biological Process	GO:0033044	regulation of chromosome organization	ISO	J:164563
Biological Process	GO:1902595	regulation of DNA replication origin binding	ISO	J:164563
Biological Process	GO:0030174	regulation of DNA-templated DNA replication initiation	ISO	J:164563
Biological Process	GO:0030174	regulation of DNA-templated DNA replication initiation	IDA	J:79742
Biological Process	GO:0030174	regulation of DNA-templated DNA replication initiation	IBA	J:265628
Biological Process	GO:0033262	regulation of nuclear cell cycle DNA replication	IDA	J:75006
Biological Process	GO:0072708	response to sorbitol	ISO	J:164563