GO Annotations Graph

• Symbol: Peli1
• Name: pellino 1
• ID: MGI:1914495

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005515	protein binding	IPI	J:263339
Molecular Function	GO:0005515	protein binding	IPI	J:176455
Molecular Function	GO:0005515	protein binding	IPI	J:152781
Molecular Function	GO:0005515	protein binding	IPI	J:152781
Molecular Function	GO:0005515	protein binding	IPI	J:281174
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0061630	ubiquitin protein ligase activity	ISO	J:164563
Molecular Function	GO:0061630	ubiquitin protein ligase activity	IBA	J:265628
Molecular Function	GO:0061630	ubiquitin protein ligase activity	IDA	J:152781
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	IDA	J:176455
Cellular Component	GO:0005634	nucleus	IDA	J:176455
Biological Process	GO:0060546	negative regulation of necroptotic process	IMP	J:263339
Biological Process	GO:0060546	negative regulation of necroptotic process	ISO	J:164563
Biological Process	GO:0032088	negative regulation of NF-kappaB transcription factor activity	IMP	J:176455
Biological Process	GO:0050868	negative regulation of T cell activation	IMP	J:176455
Biological Process	GO:0042130	negative regulation of T cell proliferation	IMP	J:176455
Biological Process	GO:0050871	positive regulation of B cell activation	IMP	J:152781
Biological Process	GO:0030890	positive regulation of B cell proliferation	IMP	J:152781
Biological Process	GO:0001819	positive regulation of cytokine production	IMP	J:152781
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	IMP	J:152781
Biological Process	GO:0031398	positive regulation of protein ubiquitination	IMP	J:152781
Biological Process	GO:0034141	positive regulation of toll-like receptor 3 signaling pathway	IMP	J:152781
Biological Process	GO:0034145	positive regulation of toll-like receptor 4 signaling pathway	IMP	J:152781
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	ISO	J:164563
Biological Process	GO:0070936	protein K48-linked ubiquitination	ISO	J:164563
Biological Process	GO:0070936	protein K48-linked ubiquitination	IBA	J:265628
Biological Process	GO:0070936	protein K48-linked ubiquitination	IDA	J:176455
Biological Process	GO:0070534	protein K63-linked ubiquitination	ISO	J:164563
Biological Process	GO:0000209	protein polyubiquitination	IMP	J:176455
Biological Process	GO:0008592	regulation of Toll signaling pathway	IEA	J:72247
Biological Process	GO:0043331	response to dsRNA	IMP	J:152781
Biological Process	GO:0032496	response to lipopolysaccharide	ISO	J:164563
Biological Process	GO:0032496	response to lipopolysaccharide	IMP	J:152781
Biological Process	GO:0042110	T cell activation	IMP	J:176455
Biological Process	GO:0042098	T cell proliferation	IMP	J:176455