GO Annotations Graph

• Symbol: Pnpla8
• Name: patatin-like phospholipase domain containing 8
• ID: MGI:1914702

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0047499	calcium-independent phospholipase A2 activity	ISO	J:164563
Molecular Function	GO:0047499	calcium-independent phospholipase A2 activity	IMP	J:246027
Molecular Function	GO:0047499	calcium-independent phospholipase A2 activity	IBA	J:265628
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0004622	lysophospholipase activity	IEA	J:72245
Molecular Function	GO:0102545	phosphatidyl phospholipase B activity	IEA	J:72245
Molecular Function	GO:0004620	phospholipase activity	IEA	J:72247
Cellular Component	GO:0005783	endoplasmic reticulum	IEA	J:60000
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0016020	membrane	IBA	J:265628
Cellular Component	GO:0005739	mitochondrion	IDA	J:120895
Cellular Component	GO:0005778	peroxisomal membrane	ISO	J:164563
Cellular Component	GO:0005777	peroxisome	IDA	J:120895
Cellular Component	GO:0005777	peroxisome	ISO	J:164563
Biological Process	GO:0019369	arachidonic acid metabolic process	ISO	J:164563
Biological Process	GO:0019369	arachidonic acid metabolic process	IBA	J:265628
Biological Process	GO:0050482	arachidonic acid secretion	ISO	J:164563
Biological Process	GO:0032048	cardiolipin metabolic process	IMP	J:246027
Biological Process	GO:0032048	cardiolipin metabolic process	ISO	J:164563
Biological Process	GO:0008219	cell death	ISO	J:164563
Biological Process	GO:0006631	fatty acid metabolic process	ISO	J:164563
Biological Process	GO:0043651	linoleic acid metabolic process	ISO	J:164563
Biological Process	GO:0016042	lipid catabolic process	IEA	J:60000
Biological Process	GO:0055088	lipid homeostasis	ISO	J:164563
Biological Process	GO:0055088	lipid homeostasis	IMP	J:120895
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0006629	lipid metabolic process	IEA	J:72247
Biological Process	GO:0034638	phosphatidylcholine catabolic process	ISO	J:164563
Biological Process	GO:0046338	phosphatidylethanolamine catabolic process	ISO	J:164563
Biological Process	GO:0001516	prostaglandin biosynthetic process	ISO	J:164563
Biological Process	GO:1900407	regulation of cellular response to oxidative stress	IMP	J:246027
Biological Process	GO:0070328	triglyceride homeostasis	ISO	J:164563
Biological Process	GO:0070328	triglyceride homeostasis	IMP	J:120895