GO Annotations Graph

• Symbol: Ufl1
• Name: UFM1 specific ligase 1
• ID: MGI:1914740

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005515	protein binding	IPI	J:217277
Molecular Function	GO:0005515	protein binding	IPI	J:272566
Molecular Function	GO:0019901	protein kinase binding	ISO	J:164563
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0061666	UFM1 ligase activity	ISO	J:164563
Molecular Function	GO:0071568	UFM1 transferase activity	IBA	J:265628
Cellular Component	GO:0005694	chromosome	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:162095
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:162095
Cellular Component	GO:0005789	endoplasmic reticulum membrane	ISO	J:164563
Cellular Component	GO:0005789	endoplasmic reticulum membrane	IBA	J:265628
Cellular Component	GO:0005789	endoplasmic reticulum membrane	ISO	J:162095
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0043005	neuron projection	IDA	J:162095
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0032991	protein-containing complex	ISO	J:162095
Cellular Component	GO:0035861	site of double-strand break	ISO	J:164563
Biological Process	GO:0000077	DNA damage checkpoint signaling	ISO	J:164563
Biological Process	GO:0006974	DNA damage response	IEA	J:60000
Biological Process	GO:0006281	DNA repair	IEA	J:60000
Biological Process	GO:0030218	erythrocyte differentiation	IMP	J:238253
Biological Process	GO:0060218	hematopoietic stem cell differentiation	IMP	J:238253
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:155856
Biological Process	GO:1903895	negative regulation of IRE1-mediated unfolded protein response	ISO	J:164563
Biological Process	GO:0032088	negative regulation of NF-kappaB transcription factor activity	ISO	J:164563
Biological Process	GO:0031397	negative regulation of protein ubiquitination	ISO	J:164563
Biological Process	GO:0010508	positive regulation of autophagy	IMP	J:238253
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:162095
Biological Process	GO:0060252	positive regulation of glial cell proliferation	IDA	J:162095
Biological Process	GO:0060252	positive regulation of glial cell proliferation	IMP	J:162095
Biological Process	GO:0032092	positive regulation of protein binding	TAS	J:217277
Biological Process	GO:1990592	protein K69-linked ufmylation	ISO	J:164563
Biological Process	GO:1990592	protein K69-linked ufmylation	IBA	J:265628
Biological Process	GO:0071569	protein ufmylation	ISO	J:164563
Biological Process	GO:0071569	protein ufmylation	ISO	J:195351
Biological Process	GO:0010468	regulation of gene expression	IMP	J:162095
Biological Process	GO:0033146	regulation of intracellular estrogen receptor signaling pathway	ISO	J:164563
Biological Process	GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process	IBA	J:265628
Biological Process	GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process	ISO	J:73065
Biological Process	GO:0032880	regulation of protein localization	ISO	J:162095
Biological Process	GO:0034976	response to endoplasmic reticulum stress	ISO	J:164563
Biological Process	GO:0034976	response to endoplasmic reticulum stress	IMP	J:238253
Biological Process	GO:0034976	response to endoplasmic reticulum stress	IBA	J:265628
Biological Process	GO:0034976	response to endoplasmic reticulum stress	ISO	J:195351
Biological Process	GO:1902065	response to L-glutamate	IMP	J:162095
Biological Process	GO:0061709	reticulophagy	ISO	J:164563