GO Annotations Graph

• Symbol: Wdr48
• Name: WD repeat domain 48
• ID: MGI:1914811

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0035800	deubiquitinase activator activity	ISO	J:164563
Molecular Function	GO:0003677	DNA binding	ISO	J:164563
Molecular Function	GO:0003690	double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0003697	single-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0043130	ubiquitin binding	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005768	endosome	IEA	J:60000
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0005764	lysosome	IEA	J:60000
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Biological Process	GO:0006974	DNA damage response	ISO	J:164563
Biological Process	GO:0006974	DNA damage response	IMP	J:206106
Biological Process	GO:0006281	DNA repair	IEA	J:60000
Biological Process	GO:0000724	double-strand break repair via homologous recombination	IBA	J:265628
Biological Process	GO:0000724	double-strand break repair via homologous recombination	IMP	J:206106
Biological Process	GO:0048568	embryonic organ development	IMP	J:206106
Biological Process	GO:0048872	homeostasis of number of cells	IMP	J:206106
Biological Process	GO:0008584	male gonad development	IMP	J:206106
Biological Process	GO:0035264	multicellular organism growth	IMP	J:206106
Biological Process	GO:1905168	positive regulation of double-strand break repair via homologous recombination	ISO	J:164563
Biological Process	GO:0050679	positive regulation of epithelial cell proliferation	IMP	J:206106
Biological Process	GO:1902525	regulation of protein monoubiquitination	IMP	J:206106
Biological Process	GO:0072520	seminiferous tubule development	IMP	J:206106
Biological Process	GO:0007338	single fertilization	IMP	J:206106
Biological Process	GO:0048705	skeletal system morphogenesis	IMP	J:206106
Biological Process	GO:0043588	skin development	IMP	J:206106
Biological Process	GO:0007283	spermatogenesis	IMP	J:206106