GO Annotations Graph

• Symbol: Tespa1
• Name: thymocyte expressed, positive selection associated 1
• ID: MGI:1914846

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0043274	phospholipase binding	IPI	J:250573
Molecular Function	GO:0005515	protein binding	IPI	J:250573
Molecular Function	GO:0005515	protein binding	IPI	J:250573
Molecular Function	GO:0005515	protein binding	IPI	J:250573
Molecular Function	GO:0005102	signaling receptor binding	IEA	J:72247
Cellular Component	GO:0008180	COP9 signalosome	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:186446
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0036398	TCR signalosome	TAS	J:250573
Cellular Component	GO:0036398	TCR signalosome	IMP	J:250573
Cellular Component	GO:0036398	TCR signalosome	IDA	J:250573
Biological Process	GO:0010387	COP9 signalosome assembly	IMP	J:186446
Biological Process	GO:0033089	positive regulation of T cell differentiation in thymus	IMP	J:186446
Biological Process	GO:0050862	positive regulation of T cell receptor signaling pathway	IMP	J:186446
Biological Process	GO:0050862	positive regulation of T cell receptor signaling pathway	IBA	J:265628
Biological Process	GO:0008104	protein localization	IMP	J:250573
Biological Process	GO:0008104	protein localization	IDA	J:250573
Biological Process	GO:0050856	regulation of T cell receptor signaling pathway	IDA	J:250573
Biological Process	GO:0050856	regulation of T cell receptor signaling pathway	IMP	J:250573
Biological Process	GO:0033077	T cell differentiation in thymus	IDA	J:250573
Biological Process	GO:0033077	T cell differentiation in thymus	IMP	J:250573
Biological Process	GO:0036399	TCR signalosome assembly	IMP	J:250573