GO Annotations Graph

• Symbol: Uchl5
• Name: ubiquitin carboxyl-terminal esterase L5
• ID: MGI:1914848

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	ISO	J:164563
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	TAS	Reactome:R-NUL-2179313
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	IBA	J:265628
Molecular Function	GO:0008234	cysteine-type peptidase activity	IEA	J:60000
Molecular Function	GO:0004866	endopeptidase inhibitor activity	ISO	J:164563
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0008233	peptidase activity	IEA	J:60000
Molecular Function	GO:0070628	proteasome binding	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-NUL-2179307
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-NUL-2179313
Cellular Component	GO:0031597	cytosolic proteasome complex	ISO	J:155856
Cellular Component	GO:0031011	Ino80 complex	ISO	J:164563
Cellular Component	GO:0031011	Ino80 complex	ISO	J:164563
Cellular Component	GO:0005730	nucleolus	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0000502	proteasome complex	IEA	J:60000
Biological Process	GO:0006338	chromatin remodeling	ISO	J:164563
Biological Process	GO:0006974	DNA damage response	IEA	J:60000
Biological Process	GO:0006310	DNA recombination	IEA	J:60000
Biological Process	GO:0006281	DNA repair	IEA	J:60000
Biological Process	GO:0048853	forebrain morphogenesis	IMP	J:166694
Biological Process	GO:0021670	lateral ventricle development	IMP	J:166694
Biological Process	GO:0030901	midbrain development	IMP	J:166694
Biological Process	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	ISO	J:164563
Biological Process	GO:0045739	positive regulation of DNA repair	IDA	J:221224
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045880	positive regulation of smoothened signaling pathway	ISO	J:164563
Biological Process	GO:1904507	positive regulation of telomere maintenance in response to DNA damage	IMP	J:221224
Biological Process	GO:0016579	protein deubiquitination	ISO	J:164563
Biological Process	GO:0016579	protein deubiquitination	IBA	J:265628
Biological Process	GO:0006508	proteolysis	IEA	J:60000
Biological Process	GO:0051726	regulation of cell cycle	ISO	J:164563
Biological Process	GO:0033044	regulation of chromosome organization	ISO	J:164563
Biological Process	GO:0006282	regulation of DNA repair	IDA	J:221224
Biological Process	GO:0006275	regulation of DNA replication	ISO	J:164563
Biological Process	GO:0060382	regulation of DNA strand elongation	ISO	J:164563
Biological Process	GO:0045995	regulation of embryonic development	IMP	J:221224
Biological Process	GO:0061136	regulation of proteasomal protein catabolic process	ISO	J:164563
Biological Process	GO:0000723	telomere maintenance	IMP	J:221224
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	IEA	J:72247