GO Annotations Graph

• Symbol: Chd8
• Name: chromodomain helicase DNA binding protein 8
• ID: MGI:1915022

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0070016	armadillo repeat domain binding	ISO	J:155856
Molecular Function	GO:0005524	ATP binding	ISO	J:164563
Molecular Function	GO:0016887	ATP hydrolysis activity	IBA	J:265628
Molecular Function	GO:0140658	ATP-dependent chromatin remodeler activity	ISO	J:164563
Molecular Function	GO:0140658	ATP-dependent chromatin remodeler activity	IBA	J:265628
Molecular Function	GO:0008013	beta-catenin binding	ISO	J:155856
Molecular Function	GO:0008013	beta-catenin binding	ISO	J:164563
Molecular Function	GO:0008013	beta-catenin binding	ISO	J:183665
Molecular Function	GO:0003682	chromatin binding	IBA	J:265628
Molecular Function	GO:0003682	chromatin binding	ISO	J:183665
Molecular Function	GO:0003682	chromatin binding	IDA	J:235128
Molecular Function	GO:0003677	DNA binding	ISO	J:164563
Molecular Function	GO:0003677	DNA binding	IDA	J:146960
Molecular Function	GO:0003677	DNA binding	IBA	J:265628
Molecular Function	GO:0004386	helicase activity	IEA	J:60000
Molecular Function	GO:0042393	histone binding	IDA	J:146960
Molecular Function	GO:0042393	histone binding	IBA	J:265628
Molecular Function	GO:0042393	histone binding	IPI	J:183665
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0035064	methylated histone binding	ISO	J:164563
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0002039	p53 binding	IPI	J:146960
Molecular Function	GO:0005515	protein binding	IPI	J:270839
Molecular Function	GO:0005515	protein binding	IPI	J:112733
Molecular Function	GO:0005515	protein binding	IPI	J:235128
Cellular Component	GO:0000785	chromatin	IBA	J:265628
Cellular Component	GO:0071339	MLL1 complex	ISO	J:164563
Cellular Component	GO:0071339	MLL1 complex	IBA	J:265628
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:146960
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Biological Process	GO:0007420	brain development	ISO	J:164563
Biological Process	GO:0007420	brain development	IBA	J:265628
Biological Process	GO:0007420	brain development	IMP	J:235128
Biological Process	GO:0006325	chromatin organization	IEA	J:60000
Biological Process	GO:0006338	chromatin remodeling	ISO	J:164563
Biological Process	GO:0006338	chromatin remodeling	IBA	J:265628
Biological Process	GO:0048565	digestive tract development	ISO	J:164563
Biological Process	GO:0048565	digestive tract development	IBA	J:265628
Biological Process	GO:0048565	digestive tract development	IMP	J:235128
Biological Process	GO:0001701	in utero embryonic development	IMP	J:92968
Biological Process	GO:0043066	negative regulation of apoptotic process	IDA	J:146960
Biological Process	GO:0043066	negative regulation of apoptotic process	IMP	J:92968
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	ISO	J:155856
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	ISO	J:164563
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	IBA	J:265628
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	ISO	J:183665
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:146960
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:155856
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IBA	J:265628
Biological Process	GO:2000270	negative regulation of fibroblast apoptotic process	IDA	J:146960
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0030178	negative regulation of Wnt signaling pathway	ISO	J:155856
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045945	positive regulation of transcription by RNA polymerase III	ISO	J:164563
Biological Process	GO:0060134	prepulse inhibition	IMP	J:235128
Biological Process	GO:0035176	social behavior	IMP	J:235128
Biological Process	GO:0001964	startle response	IMP	J:235128
Biological Process	GO:0016055	Wnt signaling pathway	IEA	J:60000